Coronavirus (COVID-19) products
Coronavirus (COVID-19) research, products and information
Coronavirus (COVID-19) Background
Novel Coronavirus disease 2019 (COVID-19) is an infectious disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The name coronavirus refers to its halo-like appearance; visually similar to a 'solar corona' around the virus particles when viewed under a microscope.
Cellular entry of COVID-19
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Image on the left adapted from the Journal of Virology paper by Heurich et al. PMID: 24227843 Click image to enlarge |
Coronavirus (COVID-19) products
Coronavirus (COVID-19) products
Coronavirus (COVID-19) products
Coronavirus (COVID-19) products
Patient-derived anti-SARS-CoV-2 recombinant antibodies
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| Catalog number | Product name | Applications | Species reactivity | Publications |
| 80063-1-RR | ACE2 Recombinant Antibody | IHC, ELISA | Human | |
| 21115-1-AP | Human ACE2 Polyclonal Antibody | IHC, WB, IP | Human, Mouse, Rat | 71 |
| 28868-1-AP | Human ACE2 Polyclonal Antibody | WB, IHC, IF, ELISA | Human, Mouse, Rat | |
| 66699-1-Ig | Human ACE2 Monoclonal Antibody | IHC, WB | Human, Mouse | 17 |
| Ag30683 | ACE2 (Binding domain) Fusion Protein | |||
| Ag15554 | ACE2 (C-terminal) Fusion Protein | |||
| 14437-1-AP | Human TMPRSS2 Polyclonal Antibody | IHC, WB | Human, Mouse, Rat | 15 |
| 18413-1-AP | Human FURIN Polyclonal Antibody | WB, IP, IHC, ELISA | Human, Mouse, Rat | 10 |
| 67481-1-Ig | Human FURIN Monoclonal Antibody | WB, IHC, ELISA | Human | |
| 60067-1-Ig | Neuropilin 1 Monoclonal antibody | WB, IF, FC, ELISA | Human, Pig | 10 |
| 11739-1-AP | ASGR1 Polyclonal antibody | WB, IP, IHC, IF, FC, ELISA | Human, Mouse, Rat | 10 |
| 66692-1-Ig | ASGR1 Monoclonal antibody | WB, ELISA | Human, Mouse, Pig | |
| Ag2310 | ASGR1 Fusion Protein |
| Catalog number | Product name | Applications | Species reactivity | Publications |
| 60099-1-Ig | Human IgA Monoclonal Antibody | WB, IHC, IF, ELISA | Human | 1 |
| 66484-1-Ig | Human IgM Monoclonal Antibody | WB, IHC, IF | Human | 1 |
| CL488-66484 | CL488-human IgM Monoclonal Antibody | WB, IHC, IF | Human | 2 |
| CL594-66484 | CL594-human IgM Monoclonal Antibody | WB, IHC, IF | Human | |
| 11016-1-AP | Human IgM Polyclonal Antibody | WB, IHC | Human | 1 |
| 10284-1-AP | Rabbit Anti-Human IgG | WB, IHC | Human | 4 |
| HRP-66484 | HRP-Conjugated Human IgM Antibody | WB, ELISA | Human |
| Catalog number | Product name | Applications | Species reactivity | Publications |
| CL488-66211 | Human CD13 Monoclonal Antibody | IF | Human | |
| 14553-1-AP | Human CD13 Polyclonal Antibody | FC, IF, IHC, WB | Human, Mouse, Rat | 5 |
| CL594-66211 | CL594-Human CD13 Monoclonal Antibody | IF | Human | |
| 66211-1-Ig | Human CD13 Monoclonal Antibody | IF, IHC, WB, | Human | 5 |
| CL488-14553 | CL488-Human CD13 Polyclonal Antibody | IF | Human, Mouse, Rat | |
| 66443-1-Ig | Human CD147 Monoclonal Antibody | IHC, WB | Human, Pig | 4 |
| CL594-66443 | CL594-Human CD147 Monoclonal Antibody | IF | Human, Pig | |
| 11989-1-AP | Human CD147 Polyclonal Antibody | IHC, IP, WB, | Human, Mouse | 19 |
| CL488-66443 | CL488-Human CD147 Monoclonal Antibody | FC, IF, | Human, Pig | |
| 21115-1-AP | Human ACE2 Polyclonal Antibody | IHC, IP, WB, | Human, Mouse, Rat | 71 |
| 66699-1-Ig | Human ACE2 Monoclonal Antibody | IHC, WB | Human | 17 |
| 20597-1-AP | Human CD9 Polyclonal Antibody | IHC, WB, FC | Human, Pig | 94 |
| 60232-1-Ig | Human CD9 Monoclonal Antibody | WB, IHC | Human, Rat | 26 |
| 60067-1-Ig | Neuropilin 1 Monoclonal Antibody | WB, IF, FC, ELISA | Human, Pig, Xenopus | 10 |
| 11739-1-AP | ASGR1 Polyclonal antibody | FC, IF, IHC, IP, WB, ELISA | Human, Mouse, Rat | 10 |
| CL488-11739 | CoraLite®488-conjugated ASGR1 Polyclonal antibody | FC, IF | Human, Mouse, Rat | |
| CL594-11739 | CoraLite®594-conjugated ASGR1 Polyclonal antibody | IF | Human, Mouse, Rat | |
| 66692-1-Ig | ASGR1 Monoclonal antibody | WB, ELISA | Human, Mouse, Pig |
| Catalog number | Product name | Applications | Species reactivity | Publications |
| 66670-1-Ig | Human IRF3 Monoclonal Antibody | IHC, WB | Human | 2 |
| 11312-1-AP | Human IRF3 Polyclonal Antibody | FC, IF, IHC, IP, WB | Human, Mouse, Rat | 85 |
| 22392-1-AP | Human IRF7 Polyclonal Antibody | IHC, IP, WB | Human | 7 |
| 23230-1-AP | Human MYD88 Polyclonal Antibody | WB | Human | 96 |
| 66992-1-Ig | Human NFKB1 Monoclonal Antibody | IF, WB | Human | 1 |
| 14220-1-AP | Human NF-κB Polyclonal Antibody | IF, IP, WB | Human, Rat | 132 |
| 15506-1-AP | Human NFKB1,p105,p50-Specific Polyclonal Antibody | WB | Human | 7 |
| 23576-1-AP | Human NFKB1 Polyclonal Antibody | IF, IHC, WB | Human | 2 |
| 15503-1-AP | Human NFKB2,p52,p100-Specific Polyclonal Antibody | IHC, WB | Human, Mouse | 3 |
| 66920-1-Ig | Human NFKB2 Monoclonal Antibody | WB | Human | |
| 51085-1-AP | Human NFKB2 Polyclonal Antibody | WB | Human, Mouse | |
| 10409-2-AP | Human NFKB2 Polyclonal Antibody | IF, IHC, IP, WB | Human, Mouse, Rat | 13 |
| CL594-66535 | CL594-human NF-κB p65 Monoclonal Antibody | IF | Human, Rat | |
| CL488-66535 | CL488-human NF-κB p65 Monoclonal Antibody | IF | Human, Rat | |
| 10745-1-AP | Human NF-κB p65 Polyclonal Antibody | FC, IF, IHC, IP, WB | Human, Mouse, Rat, Pig | 741 |
| 66535-1-Ig | Human NF-κB p65 Monoclonal Antibody | IF, IHC, WB | 86 | |
| 66545-1-Ig | Human STAT1 Monoclonal Antibody | IHC, WB | 8 | |
| 10144-2-AP | Human STAT1 Polyclonal Antibody | FC, IF, IHC, IP, WB | 70 | |
| 66485-1-Ig | Human STAT2 Monoclonal Antibody | WB | ||
| 51075-2-AP | Human STAT2 Polyclonal Antibody | IHC, WB | 1 | |
| 16674-1-AP | Human STAT2 Polyclonal Antibody | IHC, IP, WB | Human | 9 |
| 14167-1-AP | Human IRF9 Polyclonal Antibody | IF, IHC, IP, WB | Human, Mouse, Rat | 11 |
| 23288-1-AP | Human TRIF/TICAM1 Polyclonal Antibody | IHC, WB | Human | 8 |
| 19851-1-AP | Human TMEM173/STING Polyclonal Antibody | FC, IF, IHC, IP, WB | Human, Mouse, Rat | 96 |
| CL488-19851 | CL488-Human TMEM173 Polyclonal Antibody | IF | Human | |
| 66680-1-Ig | Human TMEM173/STING Monoclonal Antibody | IHC, WB | Human, Rat | 9 |
| 19771-1-AP | Human NLRP3 Polyclonal Antibody | WB | Human | 199 |
| 66902-1-Ig | Human AIM2 Monoclonal Antibody | WB | Human, Mouse, Rat | 2 |
| 11355-1-AP | Human LGP2 PolyclonalAantibody | IHC, IP, WB | Human, Mouse, Rat | 9 |
| 26416-1-AP | Human C6orf150 Polyclonal Antibody | IF, WB | Human | 17 |
| 25068-1-AP | Human DDX58 Polyclonal Antibody | IHC, IP, WB | Human | 1 |
| 20566-1-AP | Human DDX58 Polyclonal Antibody | IF, IP, WB | Human, Mouse | 18 |
| CL488-21775 | CL488-human IFIH1 Polyclonal Antibody | IF | Human, Mouse | |
| 21775-1-AP | Human IFIH1/MDA5 Polyclonal Antibody | IHC, IP, WB | Human | 24 |
| 66770-1-Ig | Human IFIH1/MDA5 Monoclonal Antibody | IHC, WB | Human | 3 |
| 19816-1-AP | Human TLR1 Polyclonal Antibody | IHC | Human, Mouse, Rat | 1 |
| 66645-1-Ig | Human TLR2 Monoclonal Antibody | WB | Human | 4 |
| 17766-1-AP | Human TLR3 Polyclonal Antibody | FC, IHC | Human | 7 |
| 66350-1-Ig | Human TLR4 Monoclonal Antibody | IHC, WB | Human, Mouse, Rat, Pig | 37 |
| 19811-1-AP | Human TLR4 Polyclonal Antibody | IHC, WB | Human, Mouse, Rat | 263 |
| 66570-1-Ig | Human TLR5 Monoclonal Antibody | WB | Human, Pig, Mouse, Rat | |
| 19810-1-AP | Human TLR5 Polyclonal Antibody | IHC, IP | Human, Mouse | 7 |
| 22240-1-AP | Human TLR6 Polyclonal Antibody | WB | Human, Mouse | 5 |
| 17232-1-AP | Human TLR7 Polyclonal Antibody | IHC, WB | Human, Mouse, Rat | 6 |
| 67317-1-Ig | Human TLR8 Monoclonal Antibody | IHC, WB | Human |
| Catalog number | Product name | Applications | Species reactivity | Publications |
| FITC-65099 | FITC-Human CD28 Monoclonal Antibody | FC | Human | |
| APC-65099 | APC-Human CD28 Monoclonal Antibody | FC | Human | |
| PE-65099 | PE-Human CD28 Monoclonal Antibody | FC | Human | |
| PE-65083 | PE-Human CD80 (B7-1) Monoclonal Antibody | FC | Human | |
| 14292-1-AP | Human CD80/B7-1 Polyclonal Antibody | FC, WB | Human, Mouse | 6 |
| 66406-1-Ig | Human CD80/B7-1 Monoclonal Antibody | IHC, WB | Human, Mouse, Pig | 10 |
| 26903-1-AP | Human CD86 (C-terminal) Polyclonal Antibody | WB | Human | 1 |
| 13395-1-AP | Human CD86 Polyclonal Antibody | FC, IF, WB | Human | 40 |
| Catalog number | Product name | Applications | Species reactivity | Publications |
| 14955-1-AP | Human OAS1 Polyclonal Antibody | IF, IHC, WB | Human, Mouse, Rat | 13 |
| 19279-1-AP | Human OAS2 Polyclonal Antibody | IF, IHC, IP, WB | Human, Mouse | 13 |
| 21915-1-AP | Human OAS3 Polyclonal Antibody | WB. IHC, IF | Human | 6 |
| Catalog number | Product name | Applications | Species reactivity | Publications |
| 10852-1-AP | Human CLTA Polyclonal Antibody | IF, IHC, IP, WB | Human, Mouse, Rat | 14 |
| 11727-3-AP | Human IFITM1 Polyclonal Antibody | FC, IHC, IP, WB | Human | 22 |
| 60074-1-Ig | Human IFITM1-Specific Monoclonal Antibody | IHC, IP, WB | Human, Rat | 48 |
| 66081-1-Ig | Human IFITM2/3 Monoclonal Antibody | FC, IF, IHC, WB | Human | 12 |
| 11714-1-AP | Human IFITM3 Polyclonal Antibody | FC, IF, IHC, IP, WB | Human, Mouse, Rat | 87 |
| 12769-1-AP | Human IFITM2 Polyclonal Antibody | IF, IHC, IP, WB | Human | 33 |
| 66137-1-Ig | Human IFITM2-specific Monoclonal Antibody | FC, WB | Human | 106 |
| 22144-1-AP | Human LY6E Polyclonal Antibody | WB, IHC, ELISA | Human, Mouse | 2 |
| 29270-1-AP | TMEM41B Polyclonal antibody | WB, IHC, ELISA | Human, Mouse | 2 |
| 20768-1-AP | TMEM41A Polyclonal antibody | WB, ELISA | Human, Mouse, Rat | 3 |
| 20489-1-AP | DAXX Polyclonal antibody | WB, IF, ELISA | Human, Mouse | 2 |
| 67879-1-Ig | DAXX Monoclonal antibody | WB, IHC, IF, ELISA | Human | |
| Ag14606 | DAXX Fusion |
| Catalog number | Product name | Applications | Species reactivity | Publications |
| 10794-1-AP | Human MTHFD1 Polyclonal Antibody | WB, IP, IHC, ELISA | Human, Mouse | 9 |
| 11246-1-AP | Human G1P3 Polyclonal Antibody | IHC | Human | 1 |
| 12604-1-AP | Human IFIT2 Polyclonal Antibody | IF, IHC, IP, WB | Human, Mouse | 31 |
| 23247-1-AP | Human IFIT1 Polyclonal Antibody | IHC, WB | Human, Mouse, Rat | 13 |
| 67208-1-Ig | Human IFIT3 Monoclonal Antibody | IHC, WB | Human | |
| 15201-1-AP | Human IFIT3 Polyclonal Antibody | IF, IHC, IP, WB | Human | 13 |
| 66646-1-Ig | Human EIF2AK2 Monoclonal Antibody | IHC, WB | Human | |
| 18244-1-AP | Human EIF2AK2, PKR Polyclonal Antibody | IF, IHC, IP, WB, | Human, Mouse, Rat | 17 |
| 15981-1-AP | Human ISG15 Polyclonal Antibody | IF, IHC, IP, WB | Human | 27 |
| 13378-1-AP | Human IFIT5 Polyclonal Antibody | IHC, IP, WB | Human | 5 |
| 27865-1-AP | Human RyDEN Polyclonal Antibody | WB | Human, Mouse, Rat | 2 |
| 13750-1-AP | Human MX1 Polyclonal Antibody | IF, IHC, IP, WB | Human, Mouse | 68 |
| 66413-1-Ig | Human ZC3HAV1 Monoclonal Antibody | IF, IHC, WB | Human | 1 |
| CL594-66413 | CL594-Human ZC3HAV1 Monoclonal Antibody | IF | Human | |
| CL488-66413 | CL488-Human ZC3HAV1 Monoclonal Antibody | IF | Human | |
| 16820-1-AP | Human ZC3HAV1 Polyclonal Antibody | IHC, IP, WB | Human, Mouse, Rat | 24 |
| 17535-1-AP | Human PARP9 Polyclonal Antibody | IHC, IP, WB | Human, Rat | 4 |
| 28089-1-AP | Human RSAD2 Polyclonal Antibody | WB | Human | 3 |
| 11963-1-AP | Human DTX3L Polyclonal Antibody | WB | Human | 2 |
| Catalog number | Product name | Applications | Species reactivity | Publications |
| 12216-1-AP | Human Cathepsin B Polyclonal Antibody | FC, IF, IHC, WB | Human, Mouse | 30 |
| 14437-1-AP | Human TMPRSS2 Polyclonal Antibody | IHC, WB | Human, Mouse, Rat | 15 |
| Catalog number | Product name | Applications | Species reactivity | Publications |
| 13744-1-AP | Human TRIM22 Polyclonal Antibody | IHC, WB | Human, Mouse | 3 |
| 10326-1-AP | Human TRIM32 Polyclonal Antibody | IF, IHC, WB | Human, Mouse, Rat | 10 |
| 10851-1-AP | Human TRIM11 Polyclonal Antibody | IHC, WB | Human | 9 |
| 11476-1-AP | Human TRIM5 Polyclonal Antibody | WB | Human, Mouse | |
| 67492-1-Ig | Human TRIM5 Monoclonal Antibody | WB | Human | |
| 13623-1-AP | Human TRIM15 Polyclonal Antibody | IF, WB | Human, Mouse | 4 |
| Catalog number | Product name | Applications | Species reactivity | Publications |
| 25404-1-AP | Human CD209 Polyclonal Antibody | WB, FC | Human | 1 |
| 17699-1-AP | Human ICAM3 Polyclonal Antibody | WB, IP, IHC, FC | Human | |
| 22003-1-AP | Human CLEC4M Polyclonal Antibody | IHC | Human | |
| 10253-2-AP | Human STAT3 Polyclonal Antibody | WB, IP, IHC, IF, FC, CoIP, ChIP | Human, Mouse, Rat, Marmoset | 212 |
| 60199-1-Ig | Human STAT3 Monoclonal Antibody | WB, IP, IHC, IF | Human, Mouse, Rat | 25 |
| 15613-1-AP | Human Fibronectin Polyclonal Antibody | WB, IP, IF | Human, Mouse, Rat, Porcine | 321 |
| 66042-1-Ig | Human Fibronectin Monoclonal Antibody | WB, IP, IHC, IF | Human, Mouse, Rat | 32 |
| 66415-1-Ig | Human AGTR1 Monoclonal Antibody | WB | Human, Mouse, Rat, Pig | |
| 25343-1-AP | Human AGTR1 Polyclonal Antibody | WB, IHC, IF | Human, Mouse, Rat | 29 |
| 12636-1-AP | Human FAK Polyclonal Antibody | WB, IP, IHC, IF | Human, Mouse, Rat | 51 |
| 66258-1-Ig | Human FAK Monoclonal Antibody | WB, IHC, IF | Human, Mouse, Rat | 21 |
| 11992-1-AP | Human Angiotensinogen Polyclonal Antibody | WB, IHC, FC | Human, Mouse | 14 |
| 14291-1-AP | Human Renin Polyclonal Antibody | WB, IHC, IF | Human, Mouse, Rat | 15 |
| 13083-1-AP | Human IFNAR1 Polyclonal Antibody | WB, IF, FC | Human | 4 |
| 10522-1-AP | Human IFNAR2 Polyclonal Antibody | WB, FC | Human | 2 |
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SARS-CoV-2 viral entry and impairment of sense of smell - Research published in ACS Chemical Neuroscience by Bilinska et al. Summary provided by Rafal Butowt, PhD, Department of Molecular Cell Genetics, L. Rydygier Collegium Medicum, Nicolaus Copernicus University (Poland), corresponding author. In the current coronavirus pandemic, a relatively large number of patients have a total loss (anosmia) or deficit of smell (hyposmia), but the mechanism is unknown. Using a mouse model, we showed that cells in the olfactory epithelium lying within the nasal cavity express host receptors that enable the SARS-CoV-2 virus to enter and infect selected cells. We identified these cells as sustentacular cells which are located near olfactory receptor neuronal dendrites containing odorant receptors. These cells are metabolically coupled with olfactory receptor neurons, participating in detoxification, odorant-desensitization and as an energy supplier to the olfactory neurons. Thus, SARS-CoV-2 infection of sustentacular cells could explain the olfactory deficient phenotype in COVID-19 patients. We also show that some proteins important for SARS-CoV-2 entry are at higher levels in older mice olfactory epithelium than in younger mice. It is speculated that sustentacular cells in the olfactory epithelium may contain more SARS-CoV-2 viral particle than cells in the oral cavity, making it easier to detect people that are infected with the virus. Butowt and colleagues used Proteintech’s ACE2 antibody (21115-1-AP) to detect expression of the target in olfactory tissue throughout the study. Proteintech’s HSP25 antibody (18284-1-AP) was used to mark sustentacular cells of the olfactory epithelium. |
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Pathogenesis of SARS-CoV-2 in human respiratory tract and conjunctiva. Research published in The Lancet Respiratory Medicine featuring Proteintech’s CC10/Uteroglobin (10490-1-AP). |
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MTHFD1 Antibody (10794-1-AP) - Anderson et al. |
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No evidence that androgen regulation of pulmonary TMPRSS2 explains sex-discordant COVID-19 outcomes TMPRSS2 Antibody (14437-1-AP) – Baratchian et al. |
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LY6E Restricts the Entry of Human Coronaviruses, including the currently pandemic 4 SARS-CoV-2 LY6E Antibody (22144-1-AP) - Zhao et al |