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ELISA Kits for SARS-COV-2 / COVID-19

Sensitive indirect and sandwich ELISA kits for detecting immunoglobulins against SARS-CoV-2 proteins

Understanding the novel coronavirus and curbing the spread of COVID-19 requires a diverse array of reagents. One of the most important tools is Enzyme-Linked Immunosorbent Assays (ELISAs), qualitative and quantitative tests for detection of different molecules. In the case of SARS-COV-2 and COVID-19, these kits detect patient immunoglobulins against viral proteins to assess immunity. Emerging evidence suggests that hyperactivity of the immune system after SARS-COV-2 infection can trigger excessive release of cytokines such as IL-6, TNF alpha and IFN gamma. This rapid immune escalation is called the cytokine storm syndrome and can lead to severe lung damage and death.

Proteintech offers well-validated and highly sensitive indirect and sandwich ELISA kits for detecting immunoglobulins against SARS-CoV-2 proteins and the cytokines involved in cytokine release syndrome. These kits are developed and validated to detect IgG and IgM immunoglobulins against Receptor Binding Domain (RBD) of SARS-CoV-2 Spike protein (S protein) and Nucleocapsid protein (N Protein). Proteintech`s wide range of cytokine-specific ELISA kits are extensively validated using in-house developed, human cell-expressed cytokines.

SARS-CoV-2 related ELISA kits

Catalog number Product name Species reactivity Sample types Format
KE30001 Anti-SARS-CoV-2 N protein Human IgG ELISA Kit Human Serum, Plasma Indirect
KE30002 Anti-SARS-CoV-2 N protein Human IgM ELISA Kit Human  Serum, Plasma Indirect 
KE30003 Anti-SARS-CoV-2 S-RBD protein Human IgG ELISA Kit Human  Serum, Plasma Indirect 
KE30004 Anti-SARS-CoV-2 S-RBD protein Human IgM ELISA Kit Human  Serum, Plasma Indirect 
KE30005 Total antibody (IgG and IgM) SARS-CoV-2 N protein ELISA Kit Human Serum, Plasma Sandwich
KE30006 Total antibody (IgG and IgM) SARS-CoV-2 S-RBD ELISA Kit Human Serum, Plasma Sandwich
KE30007 SARS-CoV-2 N protein ELISA Kit Human Serum, Plasma Sandwich

Examples of Proteintech SARS-CoV-2 ELISA Kits

AuthentiKine™ ELISA kits

To achieve superior sensitivity for human samples, these kits are built from the ground up using HumanKine® human-cell expressed cytokines and growth factors, in contrast to the industry standard of E. coli-derived proteins. 

AuthentiKine™ ELISA kit development starts with production of HumanKine® immunogens, which are human proteins with native glycosylation and processing. Due to the highest quality immunogens in the industry, the capture and detection antibodies have the highest affinity for human proteins. To best mimic the human sample analyte for optimizing the antibody parameters, HumanKine® proteins are used as the standard. This means that the antibody manufacturing and conditions for optimizing are built around using human proteins as they are in nature, resulting in unparalleled sensitivity and accuracy. 

ELISA Kit Catalog number Sample Type Sensitivity (pg/mL)
Human IL-6   ELISA kit KE00139  serum, plasma, cell culture supernatant    1.2
Human IFN-gamma  ELISA kit KE00146 serum, plasma, cell culture supernatant  0.4
Human Cystatin C  ELISA kit KE00150 serum, plasma, cell culture supernatant, urine, saliva and human milk 10.5
Human TNF-alpha  ELISA kit KE00154 serum, plasma, cell culture supernatant  8.6
Human HGF  ELISA kit KE00168 serum, plasma, cell culture supernatant 260
Human IL-10  ELISA kit KE00170 serum, plasma, cell culture supernatant 2.3
Human beta-NGF ELISA Kit KE00174 Serum, plasma, Cell culture supernatants 0.1
Human IL-27 ELISA Kit KE00182 Serum, plasma 0.1
Human M-CSF ELISA Kit  KE00184 Serum, Plasma, Cell culture supernatants, Urine, Saliva 1.1