G1P3 Polyclonal antibody

G1P3 Polyclonal Antibody for IHC, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, IHC, ELISA

Conjugate

Unconjugated

Publications

2

Cat no : 11246-1-AP

Synonyms

6 16, FAM14C, G1P3, IFI 6 16, IFI6, IFI616

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Validation Data Gallery

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  IHC staining of human breast cancer using 11246-1-AP

  Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 11246-1-AP (G1P3 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

• 

  IHC staining of human breast cancer using 11246-1-AP

  Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 11246-1-AP (G1P3 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

• 

  IHC staining of human colon using 11246-1-AP

  Immunohistochemical analysis of paraffin-embedded human colon tissue slide using 11246-1-AP (G1P3 Antibody) at dilution of 1:50 (under 40x lens).

• 

  IHC staining of human breast cancer using 11246-1-AP

  Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 11246-1-AP (G1P3 Antibody) at dilution of 1:50 (under 10x lens).

• 

  IHC staining of human breast cancer using 11246-1-AP

  Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 11246-1-AP (G1P3 Antibody) at dilution of 1:50 (under 40x lens).

• 

  IHC staining of human breast cancer using 11246-1-AP

  Immunohistochemical analysis of paraffin-embedded human breast cancer using 11246-1-AP (G1P3 antibody) at dilution of 1:50 (under 10x lens).

• 

  IHC staining of human colon using 11246-1-AP

  Immunohistochemical analysis of paraffin-embedded human colon tissue slide using 11246-1-AP (G1P3 Antibody) at dilution of 1:50 (under 10x lens).

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Tested Applications

• Positive IHC detected in: human breast cancer tissue, human colon tissue; Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0

Recommended dilution

• Immunohistochemistry (IHC): IHC : 1:50-1:500

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, Check data in validation data gallery.

Published Applications

• WB: See 1 publications below
• IHC: See 1 publications below

Product Information

11246-1-AP targets G1P3 in WB, IHC, ELISA applications and shows reactivity with human samples.

• Tested Reactivity: human
• Cited Reactivity: human
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen: G1P3 fusion protein Ag1765
• Full Name: interferon, alpha-inducible protein 6
• Calculated Molecular Weight: 13 kDa
• GenBank Accession Number: BC015603
• Gene Symbol: IFI6
• Gene ID (NCBI): 2537
• RRID: AB_2121810
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
• Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20^oC storage. 20ul sizes contain 0.1% BSA.

Background Information

G1P3, also named as IFI6, belongs to the FAM14 protein family and is localized in mitochondria. G1P3 is one of the interferon (IFN)-stimulated genes. It was reported as anti-apoptotic in myeloma, gastric and breast cancers (PMID: 29899394). G1P3 has 3 isoforms with the molecular mass of 13 kDa.

Publications

Species	Application	Title
human	WB	Nat Immunol; Exosomes mediate the cell-to-cell transmission of IFN-α-induced antiviral activity.; Authors - Li Jianhua J
human	IHC	Arthritis Rheumatol; Role and Therapeutic Potential for Targeting Fibroblast Growth Factor 10/FGFR1 in Relapsed Rheumatoid Arthritis; Authors - Xiaohui Meng