CoraLite® Plus 488-conjugated TMEM173/STING Polyclonal antibody
TMEM173/STING Polyclonal Antibody for FC (Intra), IF
Host / Isotype
Rabbit / IgG
Reactivity
human
Applications
IF, FC (Intra)
Conjugate
CoraLite® Plus 488 Fluorescent Dye
Cat no : CL488-19851
Synonyms
Validation Data Gallery
Tested Applications
Positive IF detected in | HT-29 cells, HepG2 cells |
Positive FC detected in | HepG2 cells |
Recommended dilution
Application | Dilution |
---|---|
Immunofluorescence (IF) | IF : 1:50-1:500 |
Sample-dependent, check data in validation data gallery |
Product Information
The immunogen of CL488-19851 is TMEM173/STING Fusion Protein expressed in E. coli.
Tested Reactivity | human |
Host / Isotype | Rabbit / IgG |
Class | Polyclonal |
Type | Antibody |
Immunogen | TMEM173/STING fusion protein Ag13921 |
Full Name | transmembrane protein 173 |
Calculated molecular weight | 379 aa, 42 kDa |
GenBank accession number | BC047779 |
Gene symbol | TMEM173 |
Gene ID (NCBI) | 340061 |
Conjugate | CoraLite® Plus 488 Fluorescent Dye |
Excitation/Emission maxima wavelengths | 493 nm / 522 nm |
Form | Liquid |
Purification Method | Antigen affinity purification |
Storage Buffer | PBS with 50% Glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3. |
Storage Conditions | Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA. |
Background Information
Stimulator of interferon genes (STING, also known as ERIS, MITA and MPYS, and encoded by TMEM173) is a transmembrane adaptor protein that facilitates innate immune signaling (PMID: 18724357). STING is widely expressed in various cell types such as endothelial cells, epithelial cells, T cells, macrophages, and dendritic cells (PMID: 26603901). It is predominantly located in the endoplasmic reticulum (ER). STING functions as a sensor of cytosolic DNA and promotes the production of type I interferons and pro-inflammatory cytokines.
Protocols
Product Specific Protocols | |
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IF protocol for CL Plus 488 TMEM173/STING antibody CL488-19851 | Download protocol |
FC protocol for CL Plus 488 TMEM173/STING antibody CL488-19851 | Download protocol |
Standard Protocols | |
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Click here to view our Standard Protocols |