Nano-Boosters & Nano-Labels

Higher resolution and better tissue penetration

ChromoTek's Nano-Boosters & Nano-Labels are fluorescent nanoprobes. They consist of 15 kDa small Nanobodies or VHHs, the smallest antibodies known. These single-domain alpaca antibody fragments are covalently coupled to fluorescent dyes. Due to their small size, Nano-Boosters & Nano-Labels allow for higher image resolution:

  • Better tissue penetration
  • Higher labeling density
  • Minimal linkage error: Less than 2 nm epitope-label displacement
  • GFP- and RFP-Boosters stabilize, retain, and enhance signals of fluorescent proteins
  • Recombinantly expressed and validated
  • Superior accessibility and labeling of epitopes in crowded cellular/organelle environments

Nano-Boosters & Nano-Labels can be applied in:

Explore Nano-Boosters & Nano-Labels
HeLa cells transfected with Tom70-eGFP and PCNA-mRFP and stained with GFP-Booster Alexa Fluor 488 (green) and RFP-Booster Alexa Fluor 568 (red). Images were recorded at the Core Facility Bioimaging, LMU Munich. Scale bar 10 µm.

HeLa cells transiently transfected with PCNA-mRFP and Tom 70-EGFP were subjected to one-step immunostaining with RFP-Booster Alexa Fluor® 568 (red) and GFP-Booster Alexa Fluor® 488 (green). Images were recorded at the Core Facility Bioimaging at the Biomedical Center, LMU Munich, Germany.