CD31 (PECAM-1) Antibody

A Multi-Functional Molecule

Antibody Catalog number Type Applications  
CD31 11265-1-AP Rabbit Poly ELISA, FC, IF, IHC, IP, WB 133 Publications

CD31 (PECAM-1 – platelet endothelial cell adhesion molecule-1) is an Ig gene superfamily member, composed of 6 extracellular Ig folds, with a molecular weight of 130 kDa. It is differentially glycosylated involving N-linked and O-linked glycosylation sites.

CD31 is expressed on all cells within the vascular compartment, on the surface of the endothelium. It plays a role in cell adhesion, being an efficient signaling molecule. This reflects the diverse roles of CD31 in vascular biology including angiogenesis, platelet function, thrombosis, mechanosensing of endothelial cell response to fluid shear stress, and regulation of multiple stages of leukocyte migration through venular walls.

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Loading control antibodies
GAPDH Antibody mouse monoclonal GAPDH antibody WB analysis of HeLa cells
Catalog no.: 60004-1-Ig

GAPDH is commonly used as a protein loading control in western blot due to its consistently high expression in most cell types. This enzyme participates in several cellular events such as glycolysis, DNA repair, and apoptosis.

Proteintech monoclonal GAPDH antibodies are raised against a whole-protein antigen of human origin and have over 4,960 citations.

Beta Actin Antibody (KD/KO validated) WB analysis of Jurkat cells using using beta actin antibody (66009-1-Ig)
Catalog no.: 66009-1-Ig 

Beta-actin is usually used as a loading control due to its broad and consistent expression across all eukaryotic cell types and the fact that expression levels of this protein are not affected by most experimental treatments.

66009-1-Ig has been cited in over 2,460 publications and has wide species reactivity.