|STAT3||10253-2-AP||Rabbit Poly||ELISA, ChIP, FC, IF, IHC, IP, WB|
STAT3, one of the latent cytoplasmic transcription factors, mediates the expression of a broad gene variety in response to cell stimuli, and thus plays a key role in cell growth and apoptosis. While working with Proteintech STAT3 antibodies, Yan and colleagues suggested that cancer-associated fibroblasts (CAFs) may activate the anti-apoptotic STAT3 signaling, and decrease Cisplatin-induced apoptosis, thereby promoting chemoresistance in ovarian cancer.¹ Furthermore, another research group using STAT3 antibodies suggested Arctigenin (Atn) as a promising drug candidate for designing new and effective STAT3 inhibitors.²
Immunofluorescent analysis of HeLa cells using STAT3 antibody (10253-2-AP) at a dilution of 1:25 and Rhodamine-Goat anti-Rabbit IgG.
|STAT1 - KD/KO Validated||10144-2-AP||Rabbit Poly||ELISA, FC, IF, IHC, IP, WB|
|STAT2||16674-1-AP||Rabbit Poly||ELISA, IHC, IP, WB|
|STAT3||51076-2-AP||Rabbit Poly||ELISA, IHC, IP, WB|
|STAT3 - KD/KO Validated||60199-1-Ig||Mouse Mono||ELISA, IF, IHC, IP, WB|
|STAT4||51070-2-AP||Rabbit Poly||ELISA, IF, IHC, WB|
|STAT5A||13179-1-AP||Rabbit Poly||ELISA, FC, IHC, IP, WB|
|STAT5A||66459-1-Ig||Mouse Mono||ELISA, WB|
|STAT5B||12071-1-AP||Rabbit Poly||ELISA, IF, IHC, IP, WB|
|STAT6||51073-1-AP||Rabbit Poly||ELISA, IF, IHC, WB|
1. Cancer-associated fibroblasts attenuate Cisplatininduced apoptosis in ovarian cancer cells by promoting STAT3 signaling, (PMID: 26826383).
2. Arctigenin inhibits STAT3 and exhibits anticancer potential in human triple-negative breast cancer therapy, (PMID: 27861147).