- Phare
- Validé par KD/KO
Anticorps Polyclonal de lapin anti-TLR2
TLR2 Polyclonal Antibody for ELISA
Hôte / Isotype
Lapin / IgG
Réactivité testée
Humain, rat, souris et plus (1)
Applications
WB, IP, IF, IHC, ELISA
Conjugaison
Non conjugué
N° de cat : 17236-1-AP
Synonymes
Galerie de données de validation
Applications testées
Applications publiées
| KD/KO | See 3 publications below |
| WB | See 19 publications below |
| IHC | See 6 publications below |
| IF | See 2 publications below |
| IP | See 2 publications below |
Informations sur le produit
17236-1-AP cible TLR2 dans les applications de WB, IP, IF, IHC, ELISA et montre une réactivité avec des échantillons Humain, rat, souris
| Réactivité | Humain, rat, souris |
| Réactivité citée | rat, Humain, porc, souris |
| Hôte / Isotype | Lapin / IgG |
| Clonalité | Polyclonal |
| Type | Anticorps |
| Immunogène | TLR2 Protéine recombinante Ag11079 |
| Nom complet | toll-like receptor 2 |
| Masse moléculaire calculée | 784 aa, 90 kDa |
| Numéro d’acquisition GenBank | BC033756 |
| Symbole du gène | TLR2 |
| Identification du gène (NCBI) | 7097 |
| Conjugaison | Non conjugué |
| Forme | Liquide |
| Méthode de purification | Purification par affinité contre l'antigène |
| Tampon de stockage | PBS avec azoture de sodium à 0,02 % et glycérol à 50 % pH 7,3 |
| Conditions de stockage | Stocker à -20°C. Stable pendant un an après l'expédition. L'aliquotage n'est pas nécessaire pour le stockage à -20oC Les 20ul contiennent 0,1% de BSA. |
Informations générales
TLR2, also known as CD282, is a member of the Toll-like receptor (TLR) family. TLR receptors are type I integral transmembrane glycoproteins that play a fundamental role in pathogen recognition and activation of innate immunity. TLR2 is expressed by immune cells including monocytes/macrophages, polymorphonuclear leukocytes (PMLs), and dendritic cells, and is also expressed by some no-immune cells including endothelial and epithelial cells (PMID: 21428911; 22566960). TLR2 forms heterodimers with TLR1 and TLR6, which is the initial step in a cascade of events leading to significant innate immune responses, development of adaptive immunity to pathogens, and protection from immune sequelae related to infection with these pathogens (PMID: 22566960).
Publications
| Species | Application | Title |
|---|---|---|
Mater Today Bio Intracellular hydrogelation of macrophage conjugated probiotics for hitchhiking delivery and combined treatment of colitis | ||
Mol Cancer The regulation of toll-like receptor 2 by miR-143 suppresses the invasion and migration of a subset of human colorectal carcinoma cells.
| ||
Bioorg Chem Synthesis, evaluation and molecular dynamics study of human toll-like receptor 2/6 specific monoacyl lipopeptides as candidate immunostimulants | ||
Eur J Nutr Oral intake of xanthohumol attenuates lipoteichoic acid-induced inflammatory response in human PBMCs. | ||
Front Pharmacol A Series of Genes for Predicting Responses to Anti-Tumor Necrosis Factor α Therapy in Crohn's Disease.
| ||
Front Mol Biosci Development and Validation of a 7-Gene Inflammatory Signature Forecasts Prognosis and Diverse Immune Landscape in Lung Adenocarcinoma. |
