Anticorps Polyclonal de lapin anti-SNAI2/SLUG

SNAI2/SLUG Polyclonal Antibody for WB, FC (Intra), ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris et plus (1)

Applications

WB, IHC, FC (Intra), ChIP, ELISA, IF

Conjugaison

Non conjugué

N° de cat : 12129-1-AP

Synonymes

SNAI2, WS2D, SLUGH1, SLUGH, SLUG



Applications testées

Résultats positifs en WBtissu testiculaire de souris, tissu cardiaque de rat, tissu cérébral de souris, tissu splénique de souris
Résultats positifs en FC (Intra)cellules MCF-7,

Dilution recommandée

ApplicationDilution
Western Blot (WB)WB : 1:5000-1:20000
Flow Cytometry (FC) (INTRA)FC (INTRA) : 0.20 ug per 10^6 cells in a 100 µl suspension
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Informations sur le produit

12129-1-AP cible SNAI2/SLUG dans les applications de WB, IHC, FC (Intra), ChIP, ELISA, IF et montre une réactivité avec des échantillons Humain, rat, souris

Réactivité Humain, rat, souris
Réactivité citéeHumain, poisson-zèbre, souris
Hôte / Isotype Lapin / IgG
Clonalité Polyclonal
Type Anticorps
Immunogène SNAI2/SLUG Protéine recombinante Ag2773
Nom complet snail homolog 2 (Drosophila)
Masse moléculaire calculée 268 aa, 30 kDa
Poids moléculaire observé 30 kDa
Numéro d’acquisition GenBankBC015895
Symbole du gène SLUG
Identification du gène (NCBI) 6591
Conjugaison Non conjugué
Forme Liquide
Méthode de purification Purification par affinité contre l'antigène
Tampon de stockage PBS avec azoture de sodium à 0,02 % et glycérol à 50 % pH 7,3
Conditions de stockageStocker à -20°C. Stable pendant un an après l'expédition. L'aliquotage n'est pas nécessaire pour le stockage à -20oC Les 20ul contiennent 0,1% de BSA.

Informations générales

SNAI2 belongs to the Snail family of zinc finger transcription factors, which shares an evolutionarily conserved role in mesoderm formation in vertebrates and invertebrates. It tiggers epithelial-mesenchymal transitions and has a crucial role in developmental processes. Also it is a transcriptional reperssor in mediating RAF-induced expression of TJ protein, occludin(OCLN) and subsequent oncogenic transformation of epithelial cells.

Protocole

Product Specific Protocols
WB protocol for SNAI2/SLUG antibody 12129-1-APDownload protocol
FC protocol for SNAI2/SLUG antibody 12129-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

Publications

SpeciesApplicationTitle
humanWB

J Exp Clin Cancer Res

ACTN1 promotes HNSCC tumorigenesis and cisplatin resistance by enhancing MYH9-dependent degradation of GSK-3β and integrin β1-mediated phosphorylation of FAK

Authors - Li Cui
humanWB

Cell Death Dis

UBE2E2 enhances Snail-mediated epithelial-mesenchymal transition and Nrf2-mediated antioxidant activity in ovarian cancer

Authors - Xiaoling Hong
humanWB

Mol Ther

IMPDH1/YB-1 Positive Feedback Loop Assembles Cytoophidia and Represents a Therapeutic Target in Metastatic Tumors.

Authors - Hailong Ruan
mouseIF, WB

Theranostics

Trio cooperates with Myh9 to regulate neural crest-derived craniofacial development.

Authors - Shuyu Guo
humanWB

Cell Death Dis

ZC3H15 promotes glioblastoma progression through regulating EGFR stability.

Authors - Jianbing Hou
mouseWB

Int J Biol Macromol

Fucoidan/chitosan layered PLGA nanoparticles with melatonin loading for inducing intestinal absorption and addressing triple-negative breast cancer progression

Authors - Yu-Wei Yen

Avis

The reviews below have been submitted by verified Proteintech customers who received an incentive forproviding their feedback.


FH

Udesh (Verified Customer) (08-16-2023)

Worked well in WB at 1:500

  • Applications: Western Blot
  • Primary Antibody Dilution: 1:500
  • Cell Tissue Type: Glioblastoma cells