CTGF Polyklonaler Antikörper

• Featured Product
• KD/KO Validated

CTGF Polyklonal Antikörper für ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus und mehr (3)

Anwendung

WB, IHC, IF, ELISA

Konjugation

Unkonjugiert

Publikationen

88

Kat-Nr. : 23936-1-AP

Synonyme

CCN family member 2, CCN2, CTGF, HCS24, IBP 8, IGF binding protein 8, IGFBP 8, IGFBP8, NOV2

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Galerie der Validierungsdaten

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  WB analysis of mouse skeletal muscle using 23936-1-AP

  mouse skeletal muscle tissue were subjected to SDS PAGE followed by western blot with 23936-1-AP (CTGF Antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours.

• 

  IHC staining of human gliomas using 23936-1-AP

  Immunohistochemical analysis of paraffin-embedded human gliomas tissue slide using 23936-1-AP (CTGF Antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

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  IHC staining of human gliomas using 23936-1-AP

  Immunohistochemical analysis of paraffin-embedded human gliomas tissue slide using 23936-1-AP (CTGF Antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

• 

  IHC staining of human colon cancer using 23936-1-AP

  Immunohistochemical analysis of paraffin-embedded human colon cancer tissue slide using 23936-1-AP (CTGF Antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

• 

  IHC staining of human colon cancer using 23936-1-AP

  Immunohistochemical analysis of paraffin-embedded human colon cancer tissue slide using 23936-1-AP (CTGF Antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

• 

  IF Staining of HeLa using 23936-1-AP

  Immunofluorescent analysis of (10% Formaldehyde) fixed HeLa cells using 23936-1-AP (CTGF antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IgG(H+L).

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Geprüfte Anwendungen

Empfohlene Verdünnung

Anwendung	Verdünnung
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Veröffentlichte Anwendungen

• KD/KO: See 5 publications below
• WB: See 72 publications below
• IHC: See 22 publications below
• IF: See 10 publications below
• ELISA: See 1 publications below

Produktinformation

23936-1-AP bindet in WB, IHC, IF, ELISA CTGF und zeigt Reaktivität mit human, Maus

• Getestete Reaktivität: human, Maus
• In Publikationen genannte Reaktivität: human, Hausschwein, Hund, Maus, Ratte
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: CTGF fusion protein Ag21008
• Vollständiger Name: connective tissue growth factor
• Berechnetes Molekulargewicht: 349 aa, 38 kDa
• GenBank-Zugangsnummer: BC087839
• Gene symbol: CTGF
• Gene ID (NCBI): 1490
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS mit 0.02% Natriumazid und 50% Glycerin pH 7.3.
• Lagerungsbedingungen: Bei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20^oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

CTGF, also known as CCN2 or connective tissue growth factor, is a member of the CCN family of matricellular proteins. CTGF, a cysteine-rich, matrix-associated, heparin-binding protein, is widely expressed in various human tissues and organs. CTGF has important roles in many biological processes, including cell adhesion, migration, proliferation, angiogenesis, skeletal development, and tissue wound repair, and is critically involved in fibrotic disease and several forms of cancers. In western blotting, there are three different forms of CTGF reported: monomeric forms at approximately 36-38 kDa, homodimeric forms at approximately 70 kDa, and lower molecular mass fragment forms.

Publikationen

Species	Application	Title
human	IHC	EBioMedicine; Aspirin targets P4HA2 through inhibiting NF-κB and LMCD1-AS1/let-7g to inhibit tumour growth and collagen deposition in hepatocellular carcinoma.; Authors - Tianjiao Wang
human	IHC	Cell Death Differ; O-GlcNAcylation of MORC2 at threonine 556 by OGT couples TGF-β signaling to breast cancer progression.; Authors - Ying-Ying Liu ; KD Validated
human	WB	Oncogene; Deacetylation of tumor-suppressor MST1 in Hippo pathway induces its degradation through HBXIP-elevated HDAC6 in promotion of breast cancer growth.; Authors - L Li
rat	WB	Theranostics; Crucial Role of miR-433 in Regulating Cardiac Fibrosis.; Authors - Lichan Tao
mouse	WB	Acta Pharmacol Sin; KLF4 initiates sustained YAP activation to promote renal fibrosis in mice after ischemia-reperfusion kidney injury.; Authors - Dan Xu
human	WB	Mol Ther Nucleic Acids; The RNA binding protein QKI5 suppresses ovarian cancer via downregulating transcriptional coactivator TAZ.; Authors - Tao Liu

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