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Tested Applications
| Positive IF-P detected in | mouse skin tissue |
Recommended dilution
| Application | Dilution |
|---|---|
| Immunofluorescence (IF)-P | IF-P : 1:50-1:500 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
Product Information
APC-68141 targets TACSTD2/TROP2 in IF-P applications and shows reactivity with human, mouse samples.
| Tested Reactivity | human, mouse |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Immunogen | TACSTD2/TROP2 fusion protein Ag25775 Predict reactive species |
| Full Name | tumor-associated calcium signal transducer 2 |
| Calculated Molecular Weight | 36 kDa |
| Observed Molecular Weight | 40-50 kDa |
| GenBank Accession Number | BC009409 |
| Gene Symbol | TROP2 |
| Gene ID (NCBI) | 4070 |
| Conjugate | APC Fluorescent Dye |
| Excitation/Emission Maxima Wavelengths | 650 nm / 660 nm |
| Form | Liquid |
| Purification Method | Protein A purification |
| UNIPROT ID | P09758 |
| Storage Buffer | PBS with 0.09% sodium azide and 0.5% BSA , pH 7.3 |
| Storage Conditions | Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment. |
Background Information
Trophoblast cell surface antigen 2 (TROP2), also named as TACSTD2, is a transmembrane glycoprotein. TROP2 plays a role in transducing intracellular calcium signals. It is expressed in trophoblast cells, cornea and multi-stratified epithelia. TROP2 is overexpressed in most carcinomas and is involved in cancer proliferation, migration, invasion, and metastasis. Congenital mutations of TROP2 cause a rare autosomal recessive disease which may lead to blindness-the gelatinous drop-like corneal disease (PMID: 35688908).
Protocols
| Product Specific Protocols | |
|---|---|
| IF protocol for APC TACSTD2/TROP2 antibody APC-68141 | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
