Anti-Mouse CD79b Rabbit Recombinant Antibody

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  FC experiment of mouse bone marrow cells using 98217-1-RR

  1x10^6 mouse bone marrow cells were surface stained with 0.25 ug Anti-Mouse CD79b Rabbit Recombinant Antibody (98217-1-RR, Clone: 241850D10) or Rabbit IgG Isotype Control Recombinant Antibody (98136-1-RR, Clone: 240953C9), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were co-stained with CoraLite® Plus 647 Anti-Mouse CD45R (B220) (RA3-6B2) (CL647-65139, Clone: RA3-6B2). Cells were not fixed.

• 

  FC experiment of mouse bone marrow cells using 98217-1-RR

  1x10^6 mouse bone marrow cells were surface stained with 0.25 ug Anti-Mouse CD79b Rabbit Recombinant Antibody (98217-1-RR, Clone: 241850D10)(red) or Rabbit IgG Isotype Control Recombinant Antibody (98136-1-RR, Clone: 240953C9) (blue), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were not fixed.

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  Affinity and Kinetic Characterization of 98217-1-RR

  Biolayer interferometry (BLl) kinetic assays of 98217-1-RR against Mouse CD79b were performed. The affinity constant is below 1 pM.

CD79b {ptg:Brand} Recombinant Antibody for FC

Cat No. 98217-1-RR

Clone No.241850D10

Host / Isotype

Rabbit / IgG

Reactivity

mouse

Applications

FC

Synonyms

Immunoglobulin-associated B29 protein, Ig-beta, Igb, B-cell-specific glycoprotein B29, B-cell antigen receptor complex-associated protein beta chain

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Tested Applications

• Positive FC detected in: mouse bone marrow cells

Recommended dilution

Application	Dilution
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

98217-1-RR targets CD79b in FC applications and shows reactivity with mouse samples.

• Tested Reactivity: mouse
• Host / Isotype: Rabbit / IgG
• Class: Recombinant
• Type: Antibody
• Immunogen: Recombinant protein
• Full Name: CD79B antigen
• Calculated Molecular Weight: 26 kDa
• GenBank Accession Number: NM_008339.3
• Gene Symbol: Cd79b
• Gene ID (NCBI): 15985
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purfication
• UNIPROT ID: P15530
• Storage Buffer: PBS with 0.09% sodium azide , pH 7.3
• Storage Conditions: Store at 2 - 8°C. Stable for one year after shipment.

Background Information

CD79 molecule encompasses two transmembrane proteins, CD79a and CD79b, which form a disulfide-linked heterodimer and are members of the immunoglobulin (Ig) gene superfamily (PMID: 2033258; 1375264; 2304550). CD79b molecule (also known as B29, IGB, AGM6, and Igbeta) is expressed almost exclusively on B cells and B-cell neoplasms, influencing antigen internalization and increasing antigen presentation efficiency (PMID: 7552998). CD79b mutation could be a key biomarker for DLBCL disease progression (PMID: 36182550).