CoraLite®594 Anti-Mouse CD79b Rabbit Recombinant Antibody

• 

  FC experiment of mouse bone marrow cells using CL594-98217

  1x10^6 mouse bone marrow cells were surface stained with CoraLite® Plus 488 Anti-Mouse CD45R (B220) (RA3-6B2) (CL488-65139, Clone: RA3-6B2), and 0.25ug CoraLite®594 Anti-Mouse CD79b Rabbit RecAb (CL594-98217, Clone: 241850D10) or CoraLite®594 Rabbit IgG Isotype Control RecAb (CL594-98136, Clone: 240953C9).Cells were not fixed.

• 

  FC experiment of mouse bone marrow cells using CL594-98217

  1x10^6 mouse bone marrow cells were surface stained with 0.25ug CoraLite®594 Anti-Mouse CD79b Rabbit RecAb (CL594-98217, Clone: 241850D10)(red) or CoraLite®594 Rabbit IgG Isotype Control RecAb (CL594-98136, Clone: 240953C9) (blue).Cells were not fixed.

CD79b Uni-rAb^TM Recombinant Antibody for FC

Cat No. CL594-98217

Clone No.241850D10

Host / Isotype

Rabbit / IgG

Reactivity

mouse

Applications

FC

Synonyms

241850D10, B-cell antigen receptor complex-associated protein beta chain, B-cell-specific glycoprotein B29, Igb, Ig-beta

---

Tested Applications

• Positive FC detected in: mouse bone marrow cells

Recommended dilution

Application	Dilution
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

CL594-98217 targets CD79b in FC applications and shows reactivity with mouse samples.

• Tested Reactivity: mouse
• Host / Isotype: Rabbit / IgG
• Class: Recombinant
• Type: Antibody
• Immunogen: Recombinant protein
• Full Name: CD79B antigen
• Calculated Molecular Weight: 26 kDa
• GenBank Accession Number: NM_008339.3
• Gene Symbol: Cd79b
• Gene ID (NCBI): 15985
• Conjugate: CoraLite®594 Fluorescent Dye
• Excitation/Emission Maxima Wavelengths: 588 nm / 604 nm
• Form: Liquid
• Purification Method: Protein A purification
• UNIPROT ID: P15530
• Storage Buffer: PBS with 0.09% sodium azide
• Storage Conditions: Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

Background Information

CD79 molecule encompasses two transmembrane proteins, CD79a and CD79b, which form a disulfide-linked heterodimer and are members of the immunoglobulin (Ig) gene superfamily (PMID: 2033258; 1375264; 2304550). CD79b molecule (also known as B29, IGB, AGM6, and Igbeta) is expressed almost exclusively on B cells and B-cell neoplasms, influencing antigen internalization and increasing antigen presentation efficiency (PMID: 7552998). CD79b mutation could be a key biomarker for DLBCL disease progression (PMID: 36182550).