Notable Publications - July Update
A small selection of recent notable publications from around the world
What matters to Proteintech is the success of its antibodies in the hands of scientists.
Here’s just a small selection of publications featuring Proteintech products from June - July 2017.
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1. Cell - Ciliary Hedgehog Signaling Restricts Injury-Induced Adipogenesis 4. Neuron - A Central Catecholaminergic Circuit Controls Blood Glucose Levels during Stress. |
1. Ciliary Hedgehog Signaling Restricts Injury-Induced Adipogenesis
Kopinke, Daniel et al.
Cell, Volume 170, Issue 2, p340–351.e12, 13 July 2017
Highlights:
- Fibro/adipogenic progenitors (FAPs) are dynamically ciliated during regeneration
- Ciliary Hedgehog signaling restricts FAP conversion into adipocytes through TIMP3
- TIMP3 represses injury-induced adipogenesis through inhibition of MMP14
- Removal of cilia from FAPs enhances myofiber size and formation following injury
Cited products: ARL13B & FABP4 antibodies
| KD/KO Validated | Applications: ELISA, IF, IHC, IP, WB |
| Catalog number: 17711-1-AP | 135 Publications |
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Immunofluorescent analysis of (4% PFA ) fixed MDCK cells using 17711-1-AP( ARL13B Antibody) at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit |
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2. A tripartite complex of suPAR, APOL1 risk variants and αvβ3 integrin on podocytes mediates chronic kidney disease.
Hayek, Salim et al.
Nature Medicine, doi:10.1038/nm.4362, 26 June 2017
Cited products: APOL1 ELISA kit
| Catalog number: KE00047 | Sensitivity: 0.07 ng/mL |
| Range: 0.156 ng/mL-10 ng/mL | Tests: 1 X 96 well plate |
3. Heterogeneous Ribosomes Preferentially Translate Distinct Subpools of mRNAs Genome-wide.
Shi, Zhen et al.
Molecular Cell, 67, 71–83, July 6, 2017
Highlights:
- Translating ribosomes are heterogeneous at the level of core ribosomal proteins
- Heterogeneous ribosomes preferentially translate distinct subpools of mRNAs
- RPL10A-Ribo-seq enriched mRNAs require RPL10A for their efficient translation
- IRES elements contribute to the unique translational regulation by RPL10A
Cited products: EIF3D antibody
| 8 Publications | Applications: ELISA, WB, IP, IHC, IF |
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Immunohistochemistry of paraffin-embedded human breast cancer tissue slide using 10219-1-AP( EIF3D Antibody) at dilution of 1:50 (under 40x lens) |
IF result of 10219-1-AP(anti-EIF3D) in U2OS cell (treated with 100 mM sodium arsenite to cause stress-induced translational arrest) by Dr. Nancy Kedersha. U2OS cells; stained with PTG anti-eIF3p66 in green; and counterstained with anti-eIF3b (goat polyclonal) in red; nuclei stained blue using Hoechst. |
4. A Central Catecholaminergic Circuit Controls Blood Glucose Levels during Stress.
Zhao, Zhe et al.
Neuron, Volume 95, Issue 1, p138–152.e5, 5 July 2017
Cited products: GFP tag antibody
| Catalog number: 50430-2-AP | 63 Pubications |
| Applications: ELISA, IF, IHC, IP, WB | Rabbit Polyclonal |
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IP Result of anti-GFP tag (IP:50430-2-AP, 4ug; Detection:50430-2-AP 1:5000) with Transfected HEK-293 cells lysate 300ug. |
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5. Caffeine inhibits hypothalamic A1R to excite oxytocin neuron and ameliorate dietary obesity in mice.
Wu, Liufeng et al.
Nature Communications, 8, doi:10.1038/ncomms1590427, June 2017
Cited products: MYC-tag
| Catalog number: 66004-1-Ig | 16 Publications |
| Applications: ELISA, Co-IP, IF, IP, WB | Mouse Monoclonal |
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Immunofluorescent analysis of Transfected HEK-293 cells using 66004-1-Ig( MYC-tag Antibody) at dilution of 1:25 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Mouse IgG(H+L) |
IP Result of anti-MYC-tag (IP:66004-1-Ig, 3ug; Detection:66004-1-Ig 1:5000) with Transfected HEK-293 cells lysate 500ug. |
