CD68 Monoklonaler Antikörper
CD68 Monoklonal Antikörper für ELISA
Wirt / Isotyp
Maus / IgG1
Getestete Reaktivität
human, Maus
Anwendung
WB, IHC, IF, ELISA
Konjugation
Unkonjugiert
CloneNo.
3F10E11
Kat-Nr. : 66231-1-Ig
Synonyme
Galerie der Validierungsdaten
Geprüfte Anwendungen
Empfohlene Verdünnung
| Anwendung | Verdünnung |
|---|---|
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, check data in validation data gallery | |
Veröffentlichte Anwendungen
| WB | See 1 publications below |
| IHC | See 6 publications below |
| IF | See 4 publications below |
Produktinformation
66231-1-Ig bindet in WB, IHC, IF, ELISA CD68 und zeigt Reaktivität mit human, Maus
| Getestete Reaktivität | human, Maus |
| In Publikationen genannte Reaktivität | human, Maus |
| Wirt / Isotyp | Maus / IgG1 |
| Klonalität | Monoklonal |
| Typ | Antikörper |
| Immunogen | CD68 fusion protein Ag22815 |
| Vollständiger Name | CD68 molecule |
| Berechnetes Molekulargewicht | 37 kDa |
| GenBank-Zugangsnummer | BC015557 |
| Gene symbol | CD68 |
| Gene ID (NCBI) | 968 |
| Konjugation | Unkonjugiert |
| Form | Liquid |
| Reinigungsmethode | Protein-G-Reinigung |
| Lagerungspuffer | PBS mit 0.02% Natriumazid und 50% Glycerin pH 7.3. |
| Lagerungsbedingungen | Bei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA. |
Hintergrundinformationen
CD68 is a type I transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. It belongs to the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family and primarily localizes to lysosomes and endosomes with a smaller fraction circulating to the cell surface. CD68 is also a member of the scavenger receptor family. It may play a role in phagocytic activities of tissue macrophages.
Publikationen
| Species | Application | Title |
|---|---|---|
Gastroenterology NADPH Oxidase 1 in Liver Macrophages Promotes Inflammation and Tumor Development in Mice. | ||
Redox Biol Quercetin hinders microglial activation to alleviate neurotoxicity via the interplay between NLRP3 inflammasome and mitophagy. | ||
Cancer Immunol Immunother CMTM6 expression in M2 macrophages is a potential predictor of PD-1/PD-L1 inhibitor response in colorectal cancer. | ||
Am J Respir Cell Mol Biol Lung Myofibroblast Promote Macrophage Pro-fibrotic Activity Through Lactate-induced Histone Lactylation. | ||
Front Immunol Case Report: Dendritic Cells and Macrophages Capture Sperm in Chronically Inflamed Human Epididymis. | ||
Biochem Pharmacol Glutathione S-transferases P1-mediated interleukin-6 in tumor-associated macrophages augments drug-resistance in MCF-7 breast cancer. |
