CoraLite®594-conjugated Alpha 1 antichymotrypsin Monoclonal antibody

Alpha 1 antichymotrypsin Monoclonal Antibody for IF-P
Cat No. CL594-66078
Clone No.3F2F10

Host / Isotype

Mouse / IgG2b

Reactivity

human

Applications

IF-P

Alpha Antichymotrypsin, SERPINA3, ACT, AACT, A-1-Antichymotrypsin

Formulation:  PBS and Azide
PBS and Azide
Size/Concentration: 

-/ -

Freight/Packing: -

Quantity

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Tested Applications

Positive IF-P detected inhuman tonsillitis tissue

Recommended dilution

ApplicationDilution
Immunofluorescence (IF)-PIF-P : 1:50-1:500
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

CL594-66078 targets Alpha 1 antichymotrypsin in IF-P applications and shows reactivity with human samples.

Tested Reactivity human
Host / Isotype Mouse / IgG2b
Class Monoclonal
Type Antibody
Immunogen Alpha 1 antichymotrypsin fusion protein Ag2830 Predict reactive species
Full Name serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
Calculated Molecular Weight 448 aa, 48 kDa
Observed Molecular Weight 60 kDa
GenBank Accession NumberBC010530
Gene Symbol Alpha 1 Antichymotrypsin
Gene ID (NCBI) 12
RRIDAB_2883504
Conjugate CoraLite®594 Fluorescent Dye
Excitation/Emission Maxima Wavelengths588 nm / 604 nm
Form Liquid
Purification MethodProtein A purification
UNIPROT IDP01011
Storage Buffer PBS with 50% Glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3.
Storage ConditionsStore at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Background Information

Human SerpinA3, also known as Alpha 1-antichymotrypsin (AACT), is a member of the serine protease inhibitor class, and is a plasma alpha globulin glycoprotein which increases in the blood during the inflammatory process. SerpinA3, is also an inhibitor of neutrophil cathepsin G, mast cell chymases and pancreatic chymotrypsin. SerpinA3 is produced primarily in the liver, and is identified as an acute-phase inflammatory protein. SerpinA3 deficiency has been associated with liver disease. SerpinA3 has also been implicated in the pathology of a number of devastating human diseases including chronic obstructive pulmonary disease (COPD), Parkinson's disease (PD), Alzheimer's disease (AD), Stroke, Cystic Fibrosis, Cerebral Haemorrhage and Multiple System Atrophy.

Protocols

Product Specific Protocols
IF protocol for CL594 Alpha 1 antichymotrypsin antibody CL594-66078Download protocol
Standard Protocols
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