ZEB2 Recombinant antibody, PBS Only

ZEB2 Uni-rAbTM Recombinant Antibody for WB, IHC, Indirect ELISA
Cat No. 82020-1-PBS
Clone No.1K22

Host / Isotype

Rabbit / IgG

Reactivity

Human

Applications

WB, IHC, Indirect ELISA

FLJ42816, KIAA0569, SIP 1, SIP1, Smad interacting protein 1, SMADIP1, ZEB2, ZFHX1B, ZFX1B

Formulation:  PBS Only
PBS and Azide
PBS Only
Conjugate:  Unconjugated
Size/Concentration: 

-/ -

Freight/Packing: -

Quantity

Please visit your regions distributor:


Product Information

82020-1-PBS targets ZEB2 in WB, IHC, Indirect ELISA applications and shows reactivity with Human samples.

Tested Reactivity Human
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Immunogen ZEB2 fusion protein Ag5171 Predict reactive species
Full Name zinc finger E-box binding homeobox 2
Calculated Molecular Weight 136 kDa
Observed Molecular Weight 140-150 kD
GenBank Accession NumberBC060819
Gene Symbol ZEB2
Gene ID (NCBI) 9839
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDO60315
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

Zinc finger E-box-binding homeobox (ZEB2) is a key transcription factor that acts as a multifunctional regulator during nervous system development. ZEB2 contains two zinc finger domains and a homeodomain-like sequence and interacts with the TGF-ß superfamily signaling regulators, Smads, to regulate the expression of their downstream genes. ZEB2 is expressed in the developing neural tube, as well as in neural crest cells, the hippocampus and the cerebral cortex. ZEB2 has previously been implicated in EMT, cell-cycle progression, apoptosis and senescence. ZEB2 was overexpressed in bladder, ovarian, stomach, pancreatic and squamous cell carcinoma, in the intestinal subtype of stomach cancers, and at the invasive front of CRC where EMT is most prominen. ZEB2 also mediates cell-fate decision in neuronal, T cells and hematopoietic stem cells. PMID: 27659015 )

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