WNT3A Recombinant antibody, PBS Only

WNT3A Uni-rAbTM Recombinant Antibody for IF/ICC, FC (Intra), Indirect ELISA
Cat No. 84577-4-PBS
Clone No.241993E8

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

IF/ICC, FC (Intra), Indirect ELISA

Protein Wnt-3a, Protein Wnt 3a, 241993E8

Formulation:  PBS Only
PBS and Azide
PBS Only
Conjugate:  Unconjugated
Size/Concentration: 

-/ -

Freight/Packing: -

Quantity

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Product Information

84577-4-PBS targets WNT3A in IF/ICC, FC (Intra), Indirect ELISA applications and shows reactivity with human samples.

Tested Reactivity human
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Immunogen WNT3A fusion protein Ag25051 Predict reactive species
Full Name wingless-type MMTV integration site family, member 3A
Calculated Molecular Weight 352 aa, 39 kDa
GenBank Accession NumberBC103921
Gene Symbol WNT3A
Gene ID (NCBI) 89780
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purfication
UNIPROT IDP56704
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

WNT3A belongs to wingless-type MMTV integration site family, and abnormal Wnt signalling is often associated with severe human diseases, including cancer, osteoporosis and other degenerative disorders (PMID: 20716463). Wnt3a, was shown to promote trophectoderm formation in embryonic stem cells by inducing Cdx2, one of the critical transcription factors of early trophoblast development, in an LEF-1-dependent manner. Wnt3a may also activate other β-catenin-independent cascades such as ERK or PI3K/AKT signalling, again emphasizing the complexity of the Wnt signalling network.

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