Product Information
68443-1-PBS targets VPS4B in WB, IF/ICC, IP, Indirect ELISA applications and shows reactivity with Human, mouse , rat samples.
Tested Reactivity | Human, mouse , rat |
Host / Isotype | Mouse / IgG1 |
Class | Monoclonal |
Type | Antibody |
Immunogen | VPS4B fusion protein Ag11610 Predict reactive species |
Full Name | vacuolar protein sorting 4 homolog B (S. cerevisiae) |
Calculated Molecular Weight | 444 aa, 49 kDa |
Observed Molecular Weight | ~50 kDa |
GenBank Accession Number | BC039574 |
Gene Symbol | VPS4B |
Gene ID (NCBI) | 9525 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein G purification |
UNIPROT ID | O75351 |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. |
Background Information
VPS4 (Vacuolar protein sorting-associated protein 4) is involved in intracellular protein trafficking, presumably at a late endosomal protein transport step. VPS4B is a ubiquitously expressed type I AAA+ (ATPases Associated with diverse cellular Activities) ATPase. It cooperates with its highly homologous paralog VPS4A (encoded by the VPS4A gene) to disassemble and release the Endosomal Sorting Complex Required for Transport (ESCRT) machinery. 68443-1-Ig specifically recognizes VPS4B. (PMID:31930723)