CoraLite®555-conjugated TMEM173/STING Recombinant antibody
TMEM173/STING Recombinant Antibody for IF-P
Host / Isotype
Rabbit / IgG
Reactivity
Human, Mouse, Rat
Applications
IF-P
Conjugate
CoraLite®555 Fluorescent Dye
CloneNo.
7K7
Cat no : CL555-80165
Synonyms
Validation Data Gallery
Tested Applications
Positive IF-P detected in | human tonsillitis tissue |
Recommended dilution
Application | Dilution |
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Immunofluorescence (IF)-P | IF-P : 1:50-1:500 |
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, Check data in validation data gallery. |
Product Information
CL555-80165 targets TMEM173/STING in IF-P applications and shows reactivity with Human, Mouse, Rat samples.
Tested Reactivity | Human, Mouse, Rat |
Host / Isotype | Rabbit / IgG |
Class | Recombinant |
Type | Antibody |
Immunogen | TMEM173/STING fusion protein Ag13921 |
Full Name | transmembrane protein 173 |
Calculated Molecular Weight | 379 aa, 42 kDa |
Observed Molecular Weight | 37 kDa |
GenBank Accession Number | BC047779 |
Gene Symbol | STING |
Gene ID (NCBI) | 340061 |
RRID | AB_2919709 |
Conjugate | CoraLite®555 Fluorescent Dye |
Excitation/Emission Maxima Wavelengths | 557 nm / 570nm |
Form | Liquid |
Purification Method | Protein A purification |
Storage Buffer | PBS with 50% Glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3. |
Storage Conditions | Store at -20°C. Avoid exposure to light. Aliquoting is unnecessary for -20oC storage. |
Background Information
Stimulator of interferon genes (STING, also known as ERIS, MITA and MPYS, and encoded by TMEM173) is a transmembrane adaptor protein that facilitates innate immune signaling (PMID: 18724357). STING is widely expressed in various cell types such as endothelial cells, epithelial cells, T cells, macrophages, and dendritic cells (PMID: 26603901). It is predominantly located in the endoplasmic reticulum (ER). STING functions as a sensor of cytosolic DNA and promotes the production of type I interferons and pro-inflammatory cytokines.
Protocols
Product Specific Protocols | |
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IF protocol for CL555 TMEM173/STING antibody CL555-80165 | Download protocol |
Standard Protocols | |
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Click here to view our Standard Protocols |