CoraLite®594-conjugated TBR1 Monoclonal antibody

TBR1 Monoclonal Antibody for IF

Host / Isotype

Mouse / IgG1

Reactivity

Human, rat, mouse, pig and More (1)

Applications

IF-P

Conjugate

CoraLite®594 Fluorescent Dye

Publications

1

CloneNo.

5C3A5

Cat no : CL594-66564

Synonyms

T box brain protein 1, T box, brain, 1, T brain 1, TBR 1, TBR1, TES 56

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Validation Data Gallery

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  IF Staining of mouse brain using CL594-66564

  Immunofluorescent analysis of (4% PFA) fixed mouse brain tissue using CL594-66564 (TBR1 antibody) at dilution of 1:50.

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  IF Staining of mouse brain using CL594-66564

  Immunofluorescent analysis of (4% PFA) fixed mouse brain tissue using CL594-66564 (TBR1 antibody) at dilution of 1:50.

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Tested Applications

• Positive IF-P detected in: mouse brain tissue

Recommended dilution

• Immunofluorescence (IF)-P: IF-P : 1:50-1:500

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, Check data in validation data gallery.

Published Applications

• IF: See 1 publications below

Product Information

CL594-66564 targets TBR1 in IF-P applications and shows reactivity with Human, rat, mouse, pig samples.

• Tested Reactivity: Human, rat, mouse, pig
• Cited Reactivity: human
• Host / Isotype: Mouse / IgG1
• Class: Monoclonal
• Type: Antibody
• Immunogen: TBR1 fusion protein Ag15262
• Full Name: T-box, brain, 1
• Calculated Molecular Weight: 682 aa, 74 kDa
• GenBank Accession Number: BC104844
• Gene Symbol: TBR1
• Gene ID (NCBI): 10716
• RRID: AB_2883604
• Conjugate: CoraLite®594 Fluorescent Dye
• Excitation/Emission Maxima Wavelengths: 588 nm / 604 nm
• Form: Liquid
• Purification Method: Protein G purification
• Storage Buffer: PBS with 50% Glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3.
• Storage Conditions: Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20^oC storage.

Background Information

TBR1, also named as T-box brain protein 1, is a 682 amino acid protein, which contains one T-box DNA-binding domain and localizes in the nucleus. TBR1 is expressed in the brain and as a transcriptional regulator is involved in developmental processes. TBR1 is required for normal brain development. The antibody is conjugated with CL594, Ex/Em 593 nm/614 nm.

Publications

Species	Application	Title
human	IF	Nat Commun; CBP-HSF2 structural and functional interplay in Rubinstein-Taybi neurodevelopmental disorder; Authors - Aurélie de Thonel