CoraLite® Plus 488-conjugated Synaptotagmin-1 Monoclonal antibody

Synaptotagmin-1 Monoclonal Antibody for FC (Intra)

Host / Isotype

Mouse / IgG1


Human, Mouse, Rat, Pig, Rabbit, Chicken


FC (Intra)


CoraLite® Plus 488 Fluorescent Dye



Cat no : CL488-68043


DKFZp781D2042, P65, SVP65, Synaptotagmin 1, synaptotagmin I, SYT, SYT1, SytI

Tested Applications

Positive FC detected inSH-SY5Y cells

Recommended dilution

Flow Cytometry (FC)FC : 0.40 ug per 10^6 cells in a 100 µl suspension
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

CL488-68043 targets Synaptotagmin-1 in FC (Intra) applications and shows reactivity with Human, Mouse, Rat, Pig, Rabbit, Chicken samples.

Tested Reactivity Human, Mouse, Rat, Pig, Rabbit, Chicken
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Immunogen Synaptotagmin-1 fusion protein Ag6071
Full Name synaptotagmin I
Calculated Molecular Weight 48 kDa
Observed Molecular Weight60-65 kDa
GenBank Accession NumberBC058917
Gene Symbol SYT1
Gene ID (NCBI) 6857
Conjugate CoraLite® Plus 488 Fluorescent Dye
Excitation/Emission Maxima Wavelengths493 nm / 522 nm
Form Liquid
Purification MethodProtein G purification
Storage Buffer PBS with 50% Glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3.
Storage ConditionsStore at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Background Information

The synaptotagmins are integral membrane proteins of synaptic vesicles thought to serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis (PMID: 8058779). SYT1 (synaptotagmin I) was firstly identified as a 65-kDa protein with a wide distribution in neuronal and neurosecretory tissue (PMID: 7298720). Calcium binding to SYT1 participates in triggering neurotransmitter release at the synapse (PMID: 11242035). In addition to regulating exocytosis, SYT1 has also been implicated in endocytosis and neurite outgrowth (PMID: 15492212; 11078930; 10336114).


Product Specific Protocols
FC protocol for CL Plus 488 Synaptotagmin-1 antibody CL488-68043Download protocol
Standard Protocols
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