Product Information
27556-1-PBS targets SUN2 in WB, IF/ICC, Indirect ELISA applications and shows reactivity with human, mouse samples.
Tested Reactivity | human, mouse |
Host / Isotype | Rabbit / IgG |
Class | Polyclonal |
Type | Antibody |
Immunogen | SUN2 fusion protein Ag16077 Predict reactive species |
Full Name | unc-84 homolog B (C. elegans) |
Calculated Molecular Weight | 717 aa, 80 kDa |
Observed Molecular Weight | 80-85 kDa |
GenBank Accession Number | BC111717 |
Gene Symbol | SUN2 |
Gene ID (NCBI) | 25777 |
RRID | AB_2880906 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Antigen affinity purification |
UNIPROT ID | Q9UH99 |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. |
Background Information
SUN2, also known as UNC84B, RAB5IP, belongs to the SUN (Sad1 and UNC84) protein family, which is a group of conserved proteins in eukaryotes. SUN2 is a key component of the LINC (Linker of Nucleoskeleton and Cytoskeleton) complex, which connects the nuclear lamina to the cytoskeleton. This connection is crucial for the transmission of mechanical forces across the nuclear envelope and for nuclear movement and positioning (PMID: 18396275).