Product Information
66742-1-PBS targets SRF in WB, IF/ICC, ELISA applications and shows reactivity with human, mouse, rat samples.
Tested Reactivity | human, mouse, rat |
Host / Isotype | Mouse / IgG2a |
Class | Monoclonal |
Type | Antibody |
Immunogen | SRF fusion protein Ag10386 Predict reactive species |
Full Name | serum response factor (c-fos serum response element-binding transcription factor) |
Calculated Molecular Weight | 508 aa, 52 kDa |
GenBank Accession Number | BC048211 |
Gene Symbol | SRF |
Gene ID (NCBI) | 6722 |
RRID | AB_2882090 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purification |
UNIPROT ID | P11831 |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. |
Background Information
Serum response factor (SRF) is a transcription factor that binds the serum response element (SRE), a sequence that mediates the transient response of many cellular genes to growth stimulation. SRF is required for cardiac differentiation and maturation due to the role in cardiac cell growth and muscle gene regulation. The full-length SRF protein is 67 kDa and molecular weight of cleaved fragment is 50 kDa and 20 kDa (PMID: 21769134).