SNRPD2 Monoclonal antibody, PBS Only

SNRPD2 Monoclonal Antibody for WB, Indirect ELISA

Host / Isotype

Mouse / IgG2b

Reactivity

human

Applications

WB, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

1F12B2

Cat no : 66111-1-PBS

Synonyms

Sm D2, SMD2, snRNP core protein D2, SNRPD2

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Validation Data Gallery

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  WB analysis of HeLa using 66111-1-Ig (same clone as 66111-1-PBS)

  HeLa cells were subjected to SDS PAGE followed by western blot with 66111-1-Ig (SNRPD2 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66111-1-PBS in a different storage buffer formulation.

• 

  WB analysis of MCF-7 using 66111-1-Ig (same clone as 66111-1-PBS)

  MCF7 cells were subjected to SDS PAGE followed by western blot with 66111-1-Ig (SNRPD2 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66111-1-PBS in a different storage buffer formulation.

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Product Information

66111-1-PBS targets SNRPD2 in WB, Indirect ELISA applications and shows reactivity with human samples.

• Tested Reactivity: human
• Host / Isotype: Mouse / IgG2b
• Class: Monoclonal
• Type: Antibody
• Immunogen: SNRPD2 fusion protein Ag7115
• Full Name: small nuclear ribonucleoprotein D2 polypeptide 16.5kDa
• Calculated Molecular Weight: 14 kDa
• Observed Molecular Weight: 14-16 kDa
• GenBank Accession Number: BC000486
• Gene Symbol: SNRPD2
• Gene ID (NCBI): 6633
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purification
• Storage Buffer: PBS Only
• Storage Conditions: Store at -80°C.

Background Information

Systemic lupus erythematosus is characterized by antibodies to a variety of intracellular self-antigens, such as dsDNA and Sm, and these serve as hallmarks in the diagnosis of systemic autoimmune diseases. SNRPD2 is one of Sm protein, and is required for pre-mRNA splicing, snRNP biogenesis.