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SLC31A1 Recombinant antibody, PBS Only

SLC31A1 Uni-rAbTM Recombinant Antibody for WB, ELISA

Cat No. 83844-5-PBS
Clone No.240868D10

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, ELISA

COPT1, 240868D10, CTR1, Truncated CTR1 form

Formulation:  PBS Only
PBS and Azide
PBS Only
Conjugate:  Unconjugated
Size/Concentration: 

-/ -

Freight/Packing: -

Quantity

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Product Information

83844-5-PBS targets SLC31A1 in WB, ELISA applications and shows reactivity with human samples.

Tested Reactivity human
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Immunogen SLC31A1 fusion protein Ag26601 Predict reactive species
Full Name solute carrier family 31 (copper transporters), member 1
Calculated Molecular Weight 21 kDa
Observed Molecular Weight21-23 kDa
GenBank Accession NumberBC013611
Gene Symbol SLC31A1
Gene ID (NCBI) 1317
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purfication
UNIPROT IDO15431
Storage Buffer PBS only, pH 7.3.
Storage ConditionsStore at -80°C.

Background Information

SLC31A1, also known as CTR1, COPT1 and solute carrier family 31 member 1, is a high-affinity copper transporter found in the cell membrane of human cells. It plays a crucial role in maintaining copper homeostasis within the body and functions as a homotrimer to influence dietary copper absorption in the cell membrane (PMID: 37853210; 28507097). SLC31A1 has three putative transmembrane domains, with an N-terminus located extracellularly and a C-terminus located intracellularly (PMID: 12827356). SLC31A1 can be detected a a 28 kDa band corresponding to glycosylated hCTR1 monomer, and a 24 kDa band that is unglycosylated hCTR1. In some membrane preparations a C-terminal degradation product of 17 kDa is also seen (PMID: 16135512). Additionally, SLC31A1 may also resolve as a 30 to 35 kDa and a 60 to 70 kDa protein on immunoblots, forming oligomers corresponding to the expected size of a homotrimeric complex (PMID: 12827356).

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