SDCCAG1 Monoclonal antibody, PBS Only

SDCCAG1 Monoclonal Antibody for WB, Indirect ELISA

Host / Isotype

Mouse / IgG2a

Reactivity

human

Applications

WB, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

3C8A1

Cat no : 68708-1-PBS

Synonyms

Ribosome quality control complex subunit NEMF, NY CO 1, Nuclear export mediator factor, NEMF, Homo sapiens (Human)

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Validation Data Gallery

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  WB analysis using 68708-1-Ig (same clone as 68708-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 68708-1-Ig (SDCCAG1 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68708-1-PBS in a different storage buffer formulation.

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Product Information

68708-1-PBS targets SDCCAG1 in WB, Indirect ELISA applications and shows reactivity with human samples.

• Tested Reactivity: human
• Host / Isotype: Mouse / IgG2a
• Class: Monoclonal
• Type: Antibody
• Immunogen: SDCCAG1 fusion protein Ag2467
• Full Name: serologically defined colon cancer antigen 1
• Calculated Molecular Weight: 1076 aa, 123 kDa
• Observed Molecular Weight: 130-140 kDa
• GenBank Accession Number: BC020794
• Gene Symbol: SDCCAG1
• Gene ID (NCBI): 9147
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purification
• Storage Buffer: PBS Only
• Storage Conditions: Store at -80°C.

Background Information

SDCCAG1, also named as NEMF, is a nuclear export mediator. It can be bound to translocon-engaged 60S subunits on native ER membranes. Human SDCCAG1 has been implicated in lung cancers and it may function as a tumor suppressor gene. SDCCAG1 inactivation contributes to the transformed state of human lung cancer cells (PMID:16103875, 10575219). NEMF is also regarded as a potential biomarker for the detection of active and latent TB infections (PMID: 26818387).