Product Information
67902-1-PBS targets RAB11A in WB, IF/ICC, FC (Intra), ELISA applications and shows reactivity with human, mouse, rat, pig, rabbit samples.
Tested Reactivity | human, mouse, rat, pig, rabbit |
Host / Isotype | Mouse / IgG1 |
Class | Monoclonal |
Type | Antibody |
Immunogen | RAB11A fusion protein Ag8879 Predict reactive species |
Full Name | RAB11A, member RAS oncogene family |
Calculated Molecular Weight | 216 aa, 24 kDa |
Observed Molecular Weight | 24 kDa |
GenBank Accession Number | BC013348 |
Gene Symbol | RAB11A |
Gene ID (NCBI) | 8766 |
RRID | AB_2918658 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purification |
UNIPROT ID | P62491 |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. |
Background Information
Rab11a, Rab11b and Rab25 comprise a subfamily of Rab proteins that belong to the Ras-related small GTPase protein superfamily (PMID: 8074219, PMID: 10708602). Rab11 proteins are involved in endocytosis and plasma membrane recycling in non-polarized and polarized cells ( PMID: 8638719, PMID: 8922376). Rab11a and Rab11b are ubiquitously expressed in most tissues, while Rab25 is only expressed in epithelial cells. Rab11a is known to regulate the recycling of internalized cell surface proteins and receptors from the early endosome through the trans-Golgi network (PMID: 11121436, PMID: 9600939).