PSMD8 Polyclonal antibody, PBS Only

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  WB analysis using 27504-1-AP (same clone as 27504-1-PBS)

  NIH/3T3 cells were subjected to SDS PAGE followed by western blot with 27504-1-AP (PSMD8 antibody) at dilution of 1:4000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 27504-1-PBS in a different storage buffer formulation.

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  IF Staining of U2OS using 27504-1-AP (same clone as 27504-1-PBS)

  Immunofluorescent analysis of (-20°C Ethanol) fixed U2OS cells using PSMD8 antibody (27504-1-AP) at dilution of 1:400 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). This data was developed using the same antibody clone with 27504-1-PBS in a different storage buffer formulation.

PSMD8 Polyclonal Antibody for WB, IF/ICC, Indirect ELISA

Cat No. 27504-1-PBS

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

WB, IF/ICC, Indirect ELISA

Synonyms

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Product Information

27504-1-PBS targets PSMD8 in WB, IF/ICC, Indirect ELISA applications and shows reactivity with human, mouse samples.

• Tested Reactivity: human, mouse
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen: PSMD8 fusion protein Ag26567
• Full Name: proteasome (prosome, macropain) 26S subunit, non-ATPase, 8
• Calculated Molecular Weight: 257 aa, 30 kDa
• Observed Molecular Weight: 30 kDa
• GenBank Accession Number: BC001164
• Gene Symbol: PSMD8
• Gene ID (NCBI): 5714
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• UNIPROT ID: P48556
• Storage Buffer: PBS Only
• Storage Conditions: Store at -80°C.

Background Information

The Proteasome 26S Subunit, Non-ATPase (PSMD) gene family, which includes the PSMD1 to PSMD14, regulate ubiqutinated protein breakdown in circulation as well as tumorigenesis. Studies have shown that PSMD8 interacts with the sperm adhesin AQN1 to limit polyfertilization. PSMD8 was more expressed in normal skeletal muscle, cardiac muscle, and tongue muscle; among malignant tumors, PSMD8 was expressed in ovarian cancer, testicular cancer, glioma, and melanoma(PMID:37349676).