CoraLite®555-conjugated NeutraKine® IFN Gamma Monoclonal antibody
NeutraKine® IFN Gamma Monoclonal Antibody for
Host / Isotype
Mouse / IgG1
Reactivity
Human
Applications
Conjugate
CoraLite®555 Fluorescent Dye
CloneNo.
1E10G7
Cat no : CL555-69007
Synonyms
Validation Data Gallery
Product Information
CL555-69007 targets NeutraKine® IFN Gamma in applications and shows reactivity with Human samples.
Tested Reactivity | Human |
Host / Isotype | Mouse / IgG1 |
Class | Monoclonal |
Type | Antibody |
Immunogen | NeutraKine® IFN Gamma fusion protein HZ-1301 |
Full Name | IFN gamma |
Gene Symbol | IFNG |
Gene ID (NCBI) | 3458 |
Conjugate | CoraLite®555 Fluorescent Dye |
Excitation/Emission Maxima Wavelengths | 557 nm / 570 nm |
Form | Liquid |
Purification Method | Protein G purification |
Storage Buffer | PBS with 50% Glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3. |
Storage Conditions | Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
Background Information
Interferon gamma (IFNG) is a soluble cytokine that is the only member of the type II class of interferons. It is secreted by Th1 cells, cytotoxic T cells and NK cells. The cytokine is associated with antiviral, immunoregulatory and anti-tumor properties and is a potent activator of macrophages. It plays crucial roles in pathogen clearance. Aberrant IFNG expression is associated with a number of autoinflammatory and autoimmune diseases. It has been identified in many studies as a biomarker for pleural tuberculosis (TB). Mutations in this gene are associated with aplastic anemia.
This antibody can be used to neutralize the bioactivity of Interferon gamma.