Anti-Rat NKp46/NCR1 Rabbit Recombinant Antibody, PBS Only

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  FC experiment of rat splenocytes using 98250-1-RR (same clone as 98250-1-PBS)

  1x10^6 rat splenocytes were surface stained with 0.25 ug Anti-Rat NKp46/NCR1 Rabbit Recombinant Antibody (98250-1-RR, Clone: 241811E9) or Rabbit IgG Isotype Control Recombinant Antibody (98136-1-RR, Clone: 240953C9), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were not fixed. This data was developed using the same antibody clone with 98250-1-PBS in a different storage buffer formulation.

• 

  FC experiment of rat splenocytes using 98250-1-RR (same clone as 98250-1-PBS)

  1x10^6 rat splenocytes were surface stained with 0.25 ug Anti-Rat NKp46/NCR1 Rabbit Recombinant Antibody (98250-1-RR, Clone: 241811E9) (red) or Rabbit IgG Isotype Control Recombinant Antibody (98136-1-RR, Clone: 240953C9) (blue), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were not fixed. This data was developed using the same antibody clone with 98250-1-PBS in a different storage buffer formulation.

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  Affinity and Kinetic Characterization of 98250-1-RR

  Biolayer interferometry (BLl) kinetic assays of 98250-1-RR against Rat NKp46/NCR1 were performed. The affinity constant is 0.425 nM.

NKp46/NCR1 {ptg:Brand} Recombinant Antibody for FC

Cat No. 98250-1-PBS

Clone No.241811E9

Host / Isotype

Rabbit / IgG

Reactivity

rat

Applications

FC

Synonyms

Ly94, Kilr1, CD335, Ar1, Activating receptor 1

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Product Information

98250-1-PBS targets NKp46/NCR1 in FC applications and shows reactivity with rat samples.

• Tested Reactivity: rat
• Host / Isotype: Rabbit / IgG
• Class: Recombinant
• Type: Antibody
• Immunogen: Recombinant protein
• Full Name: natural cytotoxicity triggering receptor 1
• Calculated Molecular Weight: 37kDa
• GenBank Accession Number: NM_057199.1
• Gene Symbol: NKp46/NCR1
• Gene ID (NCBI): 117547
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purfication
• UNIPROT ID: Q9Z0H5
• Storage Buffer: PBS only , pH 7.3
• Storage Conditions: Store at -80°C.

Background Information

NKp46, also known as NCR1 or CD335, is an Ig-like superfamily cell surface receptor that is highly conserved in mammals (PMID: 22021440). NKp46 is a type I transmembrane glycoprotein consisting of two extracellular Ig-like domains, a transmembrane domain, and an intracellular tail (PMID: 9730896). It is expressed on NK cells, rare T-cell subsets and a mucosal population of NKp46+ innate lymphoid cells (PMID: 9730896; 22021440). NKp46 is the major triggering receptor involved in the natural cytotoxicity (PMID: 10359120; 10092106; 15356098).