NFIL3 Monoclonal antibody, PBS Only
NFIL3 Monoclonal Antibody for ELISA, WB
Host / Isotype
Mouse / IgG1
Reactivity
pig, human
Applications
ELISA, WB
Conjugate
Unconjugated
CloneNo.
2F4B4
Cat no : 66368-1-PBS
Synonyms
Validation Data Gallery
66368-1-Ig
Product Information
66368-1-PBS targets NFIL3 in ELISA, WB applications and shows reactivity with pig, human samples.
Tested Reactivity | pig, human |
Host / Isotype | Mouse / IgG1 |
Class | Monoclonal |
Type | Antibody |
Immunogen | NFIL3 fusion protein Ag2380 |
Full Name | nuclear factor, interleukin 3 regulated |
Calculated Molecular Weight | 462 aa, 51 kDa |
Observed Molecular Weight | 50-55 kDa |
GenBank Accession Number | BC008197 |
Gene Symbol | NFIL3 |
Gene ID (NCBI) | 4783 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein G purification |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. |
Background Information
NFIL3, also named E4BP4 and IL3BP1, belongs to the bZIP family and NFIL3 subfamily. It represses transcription from promoters with activating transcription factor (ATF) sites. NFIL3 activates transcription from the interleukin-3 promoter in T-cells. It competes for the same consensus-binding site with PAR DNA-binding factors (DBP, HLF and TEF). It is a component of the circadian clock that acts as a negative regulator for the circadian expression of PER2 oscillation in the cell-autonomous core clock. NFIL3 protects pro-B cells from programmed cell death. It is a key regulator of TH2 responses(PMID:21499227).