Product Information
83005-5-PBS targets MTAP in IF/ICC, Indirect ELISA applications and shows reactivity with human samples.
Tested Reactivity | human |
Host / Isotype | Rabbit / IgG |
Class | Recombinant |
Type | Antibody |
Immunogen | MTAP fusion protein Ag2051 Predict reactive species |
Full Name | methylthioadenosine phosphorylase |
Calculated Molecular Weight | 283 aa, 31 kDa |
GenBank Accession Number | BC018625 |
Gene Symbol | MTAP |
Gene ID (NCBI) | 4507 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purfication |
UNIPROT ID | Q13126 |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. |
Background Information
MTAP is a 5-deoxy-5-methylthioadenosine (MTA) phosphorylase, converting MTA to salvageable intermediates including adenine and 5-methylthioribose-1-phosphate. MTAP is abundant in normal cells, but it is frequently found to be deleted in a variety of cancers. Its deficiency is common in cancer cell lines as well as in primary leukemia, lung cancer, melanoma, bladder cancer, gliomas and breast cancer.