INS Monoclonal antibody, PBS Only

INS Monoclonal Antibody for IHC, IF-P, Indirect ELISA
Cat No. 66198-1-PBS
Clone No.4B6A7

Host / Isotype

Mouse / IgG2a

Reactivity

human, mouse, rat

Applications

IHC, IF-P, Indirect ELISA

insulin, 4B6A7

Formulation:  PBS Only
PBS and Azide
PBS Only
Conjugate:  Unconjugated
Size/Concentration: 

-/ -

Freight/Packing: -

Quantity

Please visit your regions distributor:


Product Information

66198-1-PBS targets INS in IHC, IF-P, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Reactivity human, mouse, rat
Host / Isotype Mouse / IgG2a
Class Monoclonal
Type Antibody
Immunogen INS fusion protein Ag8630 Predict reactive species
Full Name INS
Calculated Molecular Weight 110 aa, 12 kDa
GenBank Accession NumberBC005255
Gene Symbol INS
Gene ID (NCBI) 3630
RRIDAB_2881591
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDP01308
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

INS is a peptide hormone, produced by beta cells of the pancreas, and is central to regulating carbohydrate and fat metabolism in the body. It participates in glucose utilization, protein synthesis and in the formation and storage of neutral lipids. INS is synthesized as a precursor molecule, pro-INS, which is processed prior to secretion. A- and B-peptides are joined together by a disulfide bond to form INS, while the central portion of the precursor molecule is cleaved and released as the C-peptide. Defects in INS results in type 1 diabetes mellitus. INS may also exist 36 kDa form corresponding to the hexameric INS form.

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