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- KD/KO Validated
IFITM1-Specific Monoclonal antibody, PBS Only
IFITM1-Specific Monoclonal Antibody for WB, IHC, IF/ICC, IP, ELISA
Host / Isotype
Mouse / IgG2a
Reactivity
human
Applications
WB, IHC, IF/ICC, IP, ELISA
Conjugate
Unconjugated
CloneNo.
5B5E2
Cat no : 60074-1-PBS
Synonyms
Validation Data Gallery
Product Information
60074-1-PBS targets IFITM1-Specific in WB, IHC, IF/ICC, IP, ELISA applications and shows reactivity with human samples.
Tested Reactivity | human |
Host / Isotype | Mouse / IgG2a |
Class | Monoclonal |
Type | Antibody |
Immunogen | IFITM1-Specific fusion protein Ag2320 |
Full Name | interferon induced transmembrane protein 1 (9-27) |
Calculated Molecular Weight | 14 kDa |
Observed Molecular Weight | 14-17 kDa |
GenBank Accession Number | BC000897 |
Gene Symbol | IFITM1 |
Gene ID (NCBI) | 8519 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purification |
Storage Buffer | PBS only |
Storage Conditions | Store at -80°C. |
Background Information
IFITM1(interferon induced transmembrane protein), also named DSPA2a and interferon-induced protein 17 (IFI17), belongs to the CD225 family. It has two transmembrane domain and serves as an IFN-induced antiviral protein that mediates cellular innate immunity to at least three major human pathogens, influenza A H1N1 virus, West Nile virus (WNV), and dengue virus , by inhibiting the early steps of replication. IFITM proteins are recently identified as viral restriction factors that inhibit infection mediated by the influenza A virus (IAV) hemagglutinin (HA) protein. Also they serve as important components of the innate immune system to restrict HIV-1 infection. 60074-1-Ig is a mouse monoclonal antibody which specifically recognizing IFITM1 but not IFITM2 or IFITM3.