Product Information
68313-1-PBS targets GTSE1 in WB, Indirect ELISA applications and shows reactivity with Human, Rat, mouse samples.
Tested Reactivity | Human, Rat, mouse |
Host / Isotype | Mouse / IgG1 |
Class | Monoclonal |
Type | Antibody |
Immunogen | GTSE1 fusion protein Ag32817 Predict reactive species |
Full Name | G-2 and S-phase expressed 1 |
Calculated Molecular Weight | 77 kDa |
Observed Molecular Weight | 67 kDa |
GenBank Accession Number | BC006325 |
Gene Symbol | GTSE1 |
Gene ID (NCBI) | 51512 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein G purification |
UNIPROT ID | Q9NYZ3 |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. |
Background Information
GTSE1 is only expressed in the S and G2 phases of the cell cycle, where it colocalizes with cytoplasmic tubulin and microtubules. In response to DNA damage, the encoded protein accumulates in the nucleus and binds the tumor suppressor protein p53, shutting it out of the nucleus and repressing its ability to induce apoptosis.