GABRG2 Monoclonal antibody, PBS Only

GABRG2 Monoclonal Antibody for WB, Indirect ELISA

Host / Isotype

Mouse / IgG2a

Reactivity

rat, mouse, rabbit

Applications

WB, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

1H10E1

Cat no : 68595-1-PBS

Synonyms

CAE2, ECA2, GABRG2, GEFSP3

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Validation Data Gallery

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  WB analysis using 68595-1-Ig (same clone as 68595-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 68595-1-Ig (GABRG2 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68595-1-PBS in a different storage buffer formulation.

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Product Information

68595-1-PBS targets GABRG2 in WB, Indirect ELISA applications and shows reactivity with rat, mouse, rabbit samples.

• Tested Reactivity: rat, mouse, rabbit
• Host / Isotype: Mouse / IgG2a
• Class: Monoclonal
• Type: Antibody
• Immunogen: GABRG2 fusion protein Ag5489
• Full Name: gamma-aminobutyric acid (GABA) A receptor, gamma 2
• Calculated Molecular Weight: 467 aa, 54 kDa
• Observed Molecular Weight: 40-54 kDa
• GenBank Accession Number: BC059389
• Gene Symbol: GABRG2
• Gene ID (NCBI): 2566
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purification
• Storage Buffer: PBS Only
• Storage Conditions: Store at -80°C.

Background Information

GABRG2 (gamma-aminobutyric acid type A receptor subunit gamma2), which is expected to be located in cell membrane and expressed in brain and retina. The calculated molecular weight of the protein is 54 kDa. This antibody can recognize the 43 kDa band of target (PMID:12091434). And it also has glycosylation modification. GABA is the major inhibitory neurotransmitter in the mammlian brain, where it acts at GABA-A receptors, which are ligand-gated chloride channels. GABA-A receptors are pentameric, consisting of proteins from several subunit classes: alpha, beta, gamma, delta and rho. Mutations in this gene have been associated with epilepsy and febrile seizures.