G6PC Polyclonal antibody, PBS Only

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  WB analysis using 29084-1-AP (same clone as 29084-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 29084-1-AP (G6PC antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 29084-1-PBS in a different storage buffer formulation.

G6PC Polyclonal Antibody for WB, Indirect ELISA

Cat No. 29084-1-PBS

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, Indirect ELISA

Synonyms

G6PC1, G6PT, G6Pase-alpha, G-6-Pase, G6Pase

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Product Information

29084-1-PBS targets G6PC in WB, Indirect ELISA applications and shows reactivity with human samples.

• Tested Reactivity: human
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen: G6PC fusion protein Ag30614
• Full Name: glucose-6-phosphatase, catalytic subunit
• Calculated Molecular Weight: 357 aa, 40 kDa
• Observed Molecular Weight: 40 kDa
• GenBank Accession Number: BC130478
• Gene Symbol: G6PC
• Gene ID (NCBI): 2538
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• UNIPROT ID: P35575
• Storage Buffer: PBS Only
• Storage Conditions: Store at -80°C.

Background Information

Glucose-6-phosphatase-α (G6PC) is a key enzyme in glucose homeostasis that catalyzes the hydrolysis of glucose-6-phosphate to glucose and phosphate in the terminal step of gluconeogenesis and glycogenolysis. G6PC activity is restricted to the liver , the kidney cortex and the small intestine and confers on these three organs the capacity to release glucose into the systemic circulation (PMID: 21983240).The encoded enzyme is anchored to the ER by nine transmembrane helices with the amino (N)-terminus in the lumen and the carboxyl (C)-terminus in the cytoplasm (PMID: 15542400).