Product Information
66158-1-PBS targets Fibrinogen Gamma Chain in WB, IHC, IF/ICC, ELISA applications and shows reactivity with human samples.
Tested Reactivity | human |
Host / Isotype | Mouse / IgM |
Class | Monoclonal |
Type | Antibody |
Immunogen | Fibrinogen Gamma Chain fusion protein Ag8817 Predict reactive species |
Full Name | fibrinogen gamma chain |
Calculated Molecular Weight | 453aa,52 kDa; 437aa,50 kDa |
Observed Molecular Weight | 52 kDa |
GenBank Accession Number | BC007044 |
Gene Symbol | Fibrinogen Gamma Chain |
Gene ID (NCBI) | 2266 |
RRID | AB_2881554 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purification |
UNIPROT ID | P02679 |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. |
Background Information
Fibrinogen is a soluble plasma glycoprotein synthesized in the liver. It is composed of two sets of three structurally different subunits: alpha (FGA), beta (FGB), gamma (FGG). Fibrinogen is converted by thrombin into fibrin during blood coagulation. Fibrinogen and fibrin play overlapping roles in blood clotting, fibrinolysis, cellular and matrix interactions, the inflammatory response, wound healing, and neoplasia (PMID: 16102057). FGG is the gamma chain of fibrinogen. Mutations in the gene of FGG lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia and thrombophilia.