FKBP2 Recombinant antibody, PBS Only

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  WB analysis using 84077-6-RR (same clone as 84077-6-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 84077-6-RR (FKBP2 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84077-6-PBS in a different storage buffer formulation.

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  IHC staining of mouse brain using 84077-6-RR (same clone as 84077-6-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 84077-6-RR (FKBP2 antibody) at dilution of 1:500 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 84077-6-PBS in a different storage buffer formulation.

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  IHC staining of human placenta using 84077-6-RR (same clone as 84077-6-PBS)

  Immunohistochemical analysis of paraffin-embedded human placenta tissue slide using 84077-6-RR (FKBP2 antibody) at dilution of 1:500 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 84077-6-PBS in a different storage buffer formulation.

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  Affinity and Kinetic Characterization of 84077-6-RR

  Biolayer interferometry (BLl) kinetic assays of 84077-6-RR against Human FKBP2 were performed. The affinity constant is below 1 pM.

FKBP2 Uni-rAb^TM Recombinant Antibody for WB, IHC, Indirect ELISA

Cat No. 84077-6-PBS

Clone No.241166B9

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, IHC, Indirect ELISA

Synonyms

FKBP 2, FKBP 13, FK506-binding protein 2, EC:5.2.1.8, 241166B9

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Product Information

84077-6-PBS targets FKBP2 in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

• Tested Reactivity: human, mouse, rat
• Host / Isotype: Rabbit / IgG
• Class: Recombinant
• Type: Antibody
• Immunogen: FKBP2 fusion protein Ag2255
• Full Name: FK506 binding protein 2, 13kDa
• Calculated Molecular Weight: 142 aa, 16 kDa
• Observed Molecular Weight: 13-16 kDa
• GenBank Accession Number: BC003384
• Gene Symbol: FKBP2
• Gene ID (NCBI): 2286
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purfication
• UNIPROT ID: P26885
• Storage Buffer: PBS Only
• Storage Conditions: Store at -80°C.

Background Information

FKBP2 is also named as FKBP13 and belongs to the FKBP-type PPIase family. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. FKBP2 has a 21-amino acid signal peptide and appears to be membrane-associated(PMID:1713687). It is localized to the lumen of the endoplasmic reticulum (ER). FKBP12 and FKBP13 are highly similar proteins, of molecular masses 12 kDa and 13 kDa respectively, with approx.43 % amino acid identity. The strong homology between FKBP12 and FKBP13 suggests that they may share similar biological functions, although, apart from rotamase activity, details relating to the function of either protein are scant (PMID:8373365).