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FITC Plus-conjugated EPHX2 Monoclonal antibody
EPHX2 Monoclonal Antibody for IF/ICC
Host / Isotype
Mouse / IgG2b
Reactivity
Human, Pig
Applications
IF/ICC
Conjugate
FITC Plus Fluorescent Dye
CloneNo.
4H6C8
Cat no : FITC-67322
Synonyms
Validation Data Gallery
Tested Applications
Positive IF/ICC detected in | A549 cells |
Recommended dilution
Application | Dilution |
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Immunofluorescence (IF)/ICC | IF/ICC : 1:50-1:500 |
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, Check data in validation data gallery. |
Product Information
FITC-67322 targets EPHX2 in IF/ICC applications and shows reactivity with Human, Pig samples.
Tested Reactivity | Human, Pig |
Host / Isotype | Mouse / IgG2b |
Class | Monoclonal |
Type | Antibody |
Immunogen | EPHX2 fusion protein Ag4870 |
Full Name | epoxide hydrolase 2, cytoplasmic |
Calculated Molecular Weight | 63 kDa |
Observed Molecular Weight | 56-63 kDa |
GenBank Accession Number | BC013874 |
Gene Symbol | EPHX2 |
Gene ID (NCBI) | 2053 |
Conjugate | FITC Plus Fluorescent Dye |
Excitation/Emission Maxima Wavelengths | 495 nm / 524 nm |
Form | Liquid |
Purification Method | Protein A purification |
Storage Buffer | PBS with 50% Glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3. |
Storage Conditions | Store at -20°C. Avoid exposure to light. Aliquoting is unnecessary for -20oC storage. |
Background Information
EPHX2(Epoxide hydrolase 2) acts on epoxides (alkene oxides, oxiranes) and arene oxides and plays a role in xenobiotic metabolism by degrading potentially toxic epoxides. A number of single nucleotide polymorphisms (SNPs) in human EPHX2 have been linked to cardiovascular disease risk, including increased risk of coronary heart disease, hyperlipoproteinemia, and type-2 diabetes (PMID: 14732757, 16595607, 14673705, 15845398, 17460077). It was observed in many tissues with the band of 63 kDa in the western blot. It has also been reported that the N-terminal domain might promote dimerization of EPHX2 (PMID:21553642).
Protocols
Product Specific Protocols | |
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IF protocol for FITC Plus EPHX2 antibody FITC-67322 | Download protocol |
Standard Protocols | |
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Click here to view our Standard Protocols |