Product Information
68312-1-PBS targets DYNLT1 in WB, Indirect ELISA applications and shows reactivity with Human, mouse, rat samples.
Tested Reactivity | Human, mouse, rat |
Host / Isotype | Mouse / IgG2a |
Class | Monoclonal |
Type | Antibody |
Immunogen | DYNLT1 fusion protein Ag33072 Predict reactive species |
Full Name | dynein, light chain, Tctex-type 1 |
Calculated Molecular Weight | 113 aa, 12 kDa |
Observed Molecular Weight | 12 kDa |
GenBank Accession Number | BC029412 |
Gene Symbol | DYNLT1 |
Gene ID (NCBI) | 6993 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purification |
UNIPROT ID | P63172 |
Storage Buffer | PBS only , pH 7.3 |
Storage Conditions | Store at -80°C. |
Background Information
DYNLT (or Tctex-1) was originally described as a light chain component of the dynein motor complex. Tctex-1 also has several dynein-independent functions, including roles in G protein signaling activation and neuronal growth. Tctex-1 is selectively enriched in proliferating neural progenitors of both embryonic and adult brains. Genetic knockdown of Tctex-1 in radial precursors promoted neurogenesis, indicating its implication in regulation of cortical neurogenesis. (PMID: 19448628)