DYNLT1 Monoclonal antibody, PBS Only

DYNLT1 Monoclonal Antibody for WB, Indirect ELISA

Host / Isotype

Mouse / IgG2a

Reactivity

Human, mouse, rat

Applications

WB, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

2E3D4

Cat no : 68312-1-PBS

Synonyms

CW 1, DYNLT1, Protein CW 1, TCTEL1, tctex 1, TCTEX1

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Validation Data Gallery

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  WB analysis using 68312-1-Ig (same clone as 68312-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 68312-1-Ig (DYNLT1 antibody) at dilution of 1:20000 incubated at room temperature for 1.5 hours. The membrane was stripped and reblotted with HRP-conjugated GAPDH Monoclonal antibody (HRP-60004) as loading control. This data was developed using the same antibody clone with 68312-1-PBS in a different storage buffer formulation.

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Product Information

68312-1-PBS targets DYNLT1 in WB, Indirect ELISA applications and shows reactivity with Human, mouse, rat samples.

• Tested Reactivity: Human, mouse, rat
• Host / Isotype: Mouse / IgG2a
• Class: Monoclonal
• Type: Antibody
• Immunogen: DYNLT1 fusion protein Ag33072
• Full Name: dynein, light chain, Tctex-type 1
• Calculated Molecular Weight: 113 aa, 12 kDa
• Observed Molecular Weight: 12 kDa
• GenBank Accession Number: BC029412
• Gene Symbol: DYNLT1
• Gene ID (NCBI): 6993
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purification
• Storage Buffer: PBS Only
• Storage Conditions: Store at -80°C.

Background Information

DYNLT (or Tctex-1) was originally described as a light chain component of the dynein motor complex. Tctex-1 also has several dynein-independent functions, including roles in G protein signaling activation and neuronal growth. Tctex-1 is selectively enriched in proliferating neural progenitors of both embryonic and adult brains. Genetic knockdown of Tctex-1 in radial precursors promoted neurogenesis, indicating its implication in regulation of cortical neurogenesis. (PMID: 19448628)