Anti-Human DDR1/CD167a Rabbit Recombinant Antibody, PBS Only

DDR1/CD167a Uni-rAb^TM Recombinant Antibody for FC

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

FC

Conjugate

Unconjugated

CloneNo.

241796D6

Cat no : 98200-1-PBS

Synonyms

DDR1, Cell adhesion kinase, CD167a, CD167 antigen-like family member A, CD167

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Validation Data Gallery

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  FC experiment of MCF-7 using 98200-1-RR (same clone as 98200-1-PBS)

  1x10^6 MCF-7 cells (left) or HeLa cells (right) were surface stained with 0.25 ug Anti-Human DDR1/CD167a Rabbit Recombinant Antibody (98200-1-RR, Clone: 241796D6) (red) or Rabbit IgG Isotype Control Recombinant Antibody (98136-1-RR, Clone: 240953C9) (blue), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were not fixed. This data was developed using the same antibody clone with 98200-1-PBS in a different storage buffer formulation.

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Product Information

98200-1-PBS targets DDR1/CD167a in FC applications and shows reactivity with human samples.

• Tested Reactivity: human
• Host / Isotype: Rabbit / IgG
• Class: Recombinant
• Type: Antibody
• Immunogen: FusionProtein
• Full Name: discoidin domain receptor tyrosine kinase 1
• Calculated Molecular Weight: 101kDa
• GenBank Accession Number: NM_001297654.2
• Gene Symbol: DDR1
• Gene ID (NCBI): 780
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purfication
• Storage Buffer: PBS Only
• Storage Conditions: Store at -80°C.

Background Information

DDR1, or CD167a, is a member of the receptor tyrosine kinase (RTK) family, which plays a significant role in various cellular processes including cell proliferation, adhesion, migration, and extracellular matrix (ECM) remodeling. DDR1 is known for its unique discoidin domain that allows it to bind specifically to certain collagens, initiating downstream signaling pathways that can lead to cell transformation and tumor progression. Abnormal activation of DDR1 is closely associated with the development of various solid tumors, and it has been shown that DDR1 can prevent immune cells from infiltrating triple-negative breast cancer (TNBC) and eliminate tumor cells.