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Anti-Human DDR1/CD167a Rabbit Recombinant Antibody

DDR1/CD167a Uni-rAbTM Recombinant Antibody for FC

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

FC

Conjugate

Unconjugated

CloneNo.

241796D6

Cat no : 98200-1-RR

Synonyms

DDR1, Cell adhesion kinase, CD167a, CD167 antigen-like family member A, CD167

Validation Data Gallery

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  • Flow cytometry (FC) experiment of MCF-7 cells using Anti-Human DDR1/CD167a Rabbit Recombinant Antibody (98200-1-RR)

    FC experiment of MCF-7 using 98200-1-RR

    1x10^6 MCF-7 cells (left) or HeLa cells (right) were surface stained with 0.25 ug Anti-Human DDR1/CD167a Rabbit Recombinant Antibody (98200-1-RR, Clone: 241796D6) (red) or Rabbit IgG Isotype Control Recombinant Antibody (98136-1-RR, Clone: 240953C9) (blue), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were not fixed.

Tested Applications

Positive FC detected inMCF-7 cells

Recommended dilution

ApplicationDilution
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

98200-1-RR targets DDR1/CD167a in FC applications and shows reactivity with human samples.

Tested Reactivity human
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Immunogen FusionProtein
Full Name discoidin domain receptor tyrosine kinase 1
Calculated Molecular Weight101kDa
GenBank Accession NumberNM_001297654.2
Gene Symbol DDR1
Gene ID (NCBI) 780
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purfication
Storage Buffer PBS with 0.09% sodium azide, pH 7.3.
Storage ConditionsStore at 2 - 8°C. Stable for one year after shipment.

Background Information

DDR1, or CD167a, is a member of the receptor tyrosine kinase (RTK) family, which plays a significant role in various cellular processes including cell proliferation, adhesion, migration, and extracellular matrix (ECM) remodeling. DDR1 is known for its unique discoidin domain that allows it to bind specifically to certain collagens, initiating downstream signaling pathways that can lead to cell transformation and tumor progression. Abnormal activation of DDR1 is closely associated with the development of various solid tumors, and it has been shown that DDR1 can prevent immune cells from infiltrating triple-negative breast cancer (TNBC) and eliminate tumor cells.

Protocols

Product Specific Protocols
FC protocol for DDR1/CD167a antibody 98200-1-RRDownload protocol
Standard Protocols
Click here to view our Standard Protocols