CNTN1 Monoclonal antibody, PBS Only

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  WB analysis using 68252-1-Ig (same clone as 68252-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 68252-1-Ig (CNTN1 antibody) at dilution of 1:20000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68252-1-PBS in a different storage buffer formulation.

• 

  WB analysis using 68252-1-Ig (same clone as 68252-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 68252-1-Ig (CNTN1 antibody) at dilution of 1:20000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68252-1-PBS in a different storage buffer formulation.

CNTN1 Monoclonal Antibody for WB, Indirect ELISA

Cat No. 68252-1-PBS

Clone No.1C1D4

Host / Isotype

Mouse / IgG1

Reactivity

Human, pig, rabbit

Applications

WB, Indirect ELISA

Synonyms

CNTN1, contactin 1, F3, Glycoprotein gp135, GP135, Neural cell surface protein F3

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Product Information

68252-1-PBS targets CNTN1 in WB, Indirect ELISA applications and shows reactivity with Human, pig, rabbit samples.

• Tested Reactivity: Human, pig, rabbit
• Host / Isotype: Mouse / IgG1
• Class: Monoclonal
• Type: Antibody
• Immunogen: CNTN1 fusion protein Ag5030
• Full Name: contactin 1
• Calculated Molecular Weight: 1018 aa, 113 kDa
• Observed Molecular Weight: 130-135 kDa
• GenBank Accession Number: BC036569
• Gene Symbol: CNTN1
• Gene ID (NCBI): 1272
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein G purification
• UNIPROT ID: Q12860
• Storage Buffer: PBS Only
• Storage Conditions: Store at -80°C.

Background Information

Contactin-1 (CNTN1), also known as Glycoprotein gp135 or Neural cell surface protein F3, is a neuronal cell adhesion molecule of the immunoglobulin superfamily (PMID: 3049624). It consists of six Ig domains, four fibronectin-like motifs, and a glycosylphosphatidylinositol (GPI)-moiety. Expressed by the central and peripheral neurons, CNTN1 contributes to the formation and function of neuronal connections. It plays a role in axon extension and formation of septate-like junctions between axons and myelinating glial cells (PMID: 23724143). In addition, acting as a ligand for Notch, CNTN1 initiates a NOTCH/DTX1 signaling pathway that promotes oligodendrocyte maturation and myelination (PMID: 14567914).