Product Information
66343-1-PBS targets CLIC4 in WB, IHC, IF/ICC, FC (Intra), Indirect ELISA applications and shows reactivity with human, rat, pig samples.
Tested Reactivity | human, rat, pig |
Host / Isotype | Mouse / IgG1 |
Class | Monoclonal |
Type | Antibody |
Immunogen | CLIC4 fusion protein Ag2942 Predict reactive species |
Full Name | chloride intracellular channel 4 |
Calculated Molecular Weight | 253 aa, 29 kDa |
Observed Molecular Weight | 29 kDa |
GenBank Accession Number | BC012444 |
Gene Symbol | CLIC4 |
Gene ID (NCBI) | 25932 |
RRID | AB_2881723 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein G purification |
UNIPROT ID | Q9Y696 |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. |
Background Information
Chloride channels are a diverse group of proteins that regulate fundamental cellular processes including stabilization of cell membrane potential, transepithelial transport, maintenance of intracellular pH, and regulation of cell volume. CLIC4 is a p53- and tumor necrosis factor alpha-regulated cytoplasmic and mitochondrial protein that belongs to the CLIC family of intracellular chloride channels. CLICs have actions distinct from traditional cell membrane chloride channels, including formation of ion channels in intracellular organelles and roles in membrane trafficking, apoptosis, and cell differentiation.