Product Information
67843-1-PBS targets CIP2A in WB, IF/ICC, Indirect ELISA applications and shows reactivity with Human, rat samples.
Tested Reactivity | Human, rat |
Host / Isotype | Mouse / IgG1 |
Class | Monoclonal |
Type | Antibody |
Immunogen | CIP2A fusion protein Ag19598 Predict reactive species |
Full Name | KIAA1524 |
Calculated Molecular Weight | 905 aa, 102 kDa |
Observed Molecular Weight | 102 kDa |
GenBank Accession Number | BC130564 |
Gene Symbol | CIP2A |
Gene ID (NCBI) | 57650 |
RRID | AB_2918605 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein G purification |
UNIPROT ID | Q8TCG1 |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. |
Background Information
Cancerous inhibitor of protein phosphatase 2A (CIP2A) was originally identified as a cellular protein phosphatase 2A (PP2A) inhibitor, and has been shown to control oncogenic cellular signals by suppressing the tumor suppressor PP2A. CIP2A overexpression has been found in several human malignancies including breast cancer, hepatocellular carcinoma, gastric cancer, head and neck cancer, colon cancer, prostate cancer and non-small cell lung cancer. CIP2A is a 83~102 kDa cytoplasmic protein. ( PMID: 26824320, PMID: 25458953, PMID: 29720672)