Anti-Human CD94 Rabbit Recombinant Antibody, PBS Only

CD94 Uni-rAb^TM Recombinant Antibody for FC

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

FC

Conjugate

Unconjugated

CloneNo.

241704E11

Cat no : 98172-1-PBS

Synonyms

NK cell receptor, KP43, KLRD1, Killer cell lectin-like receptor subfamily D member 1, 241704E11

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Validation Data Gallery

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  FC experiment of human peripheral blood leukocytes using 98172-1-RR (same clone as 98172-1-PBS)

  1x10^6 human peripheral blood leukocytes were surface stained with 0.25 ug Anti-Human CD94 Rabbit Recombinant Antibody (98172-1-RR, Clone:241704E11) or Isotype Control, and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were then stained with CoraLite® Plus 647 Anti-Human NCAM1/CD56. Cells were incubated with FC Receptor Block prior to staining. Cells were not fixed. This data was developed using the same antibody clone with 98172-1-PBS in a different storage buffer formulation.

• 

  FC experiment of human peripheral blood leukocytes using 98172-1-RR (same clone as 98172-1-PBS)

  1x10^6 human peripheral blood leukocytes were surface stained with 0.25 ug Anti-Human CD94 Rabbit Recombinant Antibody (98172-1-RR, Clone: 241704E11) (red) or Isotype Control (blue), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were incubated with FC Receptor Block prior to staining. Cells were not fixed. This data was developed using the same antibody clone with 98172-1-PBS in a different storage buffer formulation.

• 

  Affinity and Kinetic Characterization of 98172-1-RR

  Biolayer interferometry (BLl) kinetic assays of 98172-1-RR against Human CD94 were performed. The affinity constant is below 3.17 nM.

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Product Information

98172-1-PBS targets CD94 in FC applications and shows reactivity with human samples.

• Tested Reactivity: human
• Host / Isotype: Rabbit / IgG
• Class: Recombinant
• Type: Antibody
• Immunogen: Recombinant Protein
• Full Name: killer cell lectin-like receptor subfamily D, member 1
• Calculated Molecular Weight: 179 aa, 20 kDa
• GenBank Accession Number: BC028009
• Gene Symbol: CD94
• Gene ID (NCBI): 3824
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purfication
• Storage Buffer: PBS Only
• Storage Conditions: Store at -80°C.

Background Information

CD94, also known as KLRD1, is a membrane protein that is preferentially expressed on NK cells. CD94 can form disulfide-bonded heterodimers with NKG2 family members. The CD94/NKG2A heterodimer constitutes an inhibitory receptor that recognizes HLA-E.