Anti-Human CD94 Rabbit Recombinant Antibody, PBS Only

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  FC experiment of human peripheral blood leukocytes using 98172-1-RR (same clone as 98172-1-PBS)

  1x10^6 human peripheral blood leukocytes were surface stained with 0.25 ug Anti-Human CD94 Rabbit Recombinant Antibody (98172-1-RR, Clone:241704E11) or Isotype Control, and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were then stained with CoraLite® Plus 647 Anti-Human NCAM1/CD56. Cells were incubated with FC Receptor Block prior to staining. Cells were not fixed. This data was developed using the same antibody clone with 98172-1-PBS in a different storage buffer formulation.

• 

  FC experiment of human peripheral blood leukocytes using 98172-1-RR (same clone as 98172-1-PBS)

  1x10^6 human peripheral blood leukocytes were surface stained with 0.25 ug Anti-Human CD94 Rabbit Recombinant Antibody (98172-1-RR, Clone: 241704E11) (red) or Isotype Control (blue), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were incubated with FC Receptor Block prior to staining. Cells were not fixed. This data was developed using the same antibody clone with 98172-1-PBS in a different storage buffer formulation.

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  Affinity and Kinetic Characterization of 98172-1-RR

  Biolayer interferometry (BLl) kinetic assays of 98172-1-RR against Human CD94 were performed. The affinity constant is below 3.17 nM.

CD94 Uni-rAb^TM Recombinant Antibody for FC

Cat No. 98172-1-PBS

Clone No.241704E11

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

FC

Synonyms

241704E11, Killer cell lectin-like receptor subfamily D member 1, KLRD1, KP43, NK cell receptor

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Product Information

98172-1-PBS targets CD94 in FC applications and shows reactivity with human samples.

• Tested Reactivity: human
• Host / Isotype: Rabbit / IgG
• Class: Recombinant
• Type: Antibody
• Immunogen: Recombinant Protein
• Full Name: killer cell lectin-like receptor subfamily D, member 1
• Calculated Molecular Weight: 179 aa, 20 kDa
• GenBank Accession Number: BC028009
• Gene Symbol: CD94
• Gene ID (NCBI): 3824
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purfication
• UNIPROT ID: Q13241
• Storage Buffer: PBS only, pH 7.3.
• Storage Conditions: Store at -80°C.

Background Information

CD94, also known as the killer cell lectin-like receptor (KLR) family member, is a type II integral membrane protein related to the C-type lectin superfamily. It is specifically expressed on natural killer (NK) cells and a subset of T cells, and plays a crucial role in stimulating NK cell cytolysis and the release of tumor necrosis factor. CD94 can form heterodimers with different NKG2 proteins (e.g., NKG2A, NKG2C, NKG2E, or NKG2F) to balance the function of NK cells and CD8+ T cells.