FITC Plus Anti-Mouse CD48 (HM48-1)

CD48 Monoclonal Antibody for FC
Cat No. FITC-65227
Clone No.HM48-1

Host / Isotype

Armenian Hamster / IgG

Reactivity

mouse

Applications

FC

MEM 102, HM48-1, CD48 antigen, BLAST1, BLAST 1

Formulation:  PBS and Azide
PBS and Azide
Size/Concentration: 

-/ -

Freight/Packing: -

Quantity

Please visit your regions distributor:


Tested Applications

Positive FC detected inmouse splenocytes

Recommended dilution

ApplicationDilution
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

FITC-65227 targets CD48 in FC applications and shows reactivity with mouse samples.

Tested Reactivity mouse
Host / Isotype Armenian Hamster / IgG
Class Monoclonal
Type Antibody
Immunogen Mouse T lymphoma MBL-2 Predict reactive species
Full Name CD48 antigen
GenBank Accession NumberBC060977
Gene Symbol Cd48
Gene ID (NCBI) 12506
RRIDAB_2924144
Conjugate FITC Plus Fluorescent Dye
Excitation/Emission Maxima Wavelengths495 nm / 524 nm
Form Liquid
Purification MethodAffinity purification
UNIPROT IDP18181
Storage Buffer PBS with 0.09% sodium azide.
Storage ConditionsStore at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

Background Information

Signaling lymphocytic activation molecule family 2 (SLAMF2, CD48) is an adhesion and costimulatory molecule expressed constitutively on most hematopoietic cells, particularly in antigen-presenting cells (APC). CD48 is expressed on all the hematopoietic cells, both in humans and mice, except for murine neutrophils and long-term HSC. CD48 exists as both a membrane-bound (mCD48) and a soluble (sCD48) form. CD48 can activate T cells, antigen-presenting cells and granulocytes, by binding to CD2 or bacterial FimH, and through cell intrinsic effects. Interactions between CD48 and its high-affinity ligand CD244 are more complex, with both stimulatory and inhibitory outcomes. CD48 expression is increased in autoimmunity and allergy diseases, and anti-CD48 monoclonal antibodies have been shown to attenuate experimental autoimmune encephalomyelitis.

Protocols

Product Specific Protocols
FC protocol for FITC Plus CD48 antibody FITC-65227Download protocol
Standard Protocols
Click here to view our Standard Protocols
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