CoraLite®594 Anti-Rat CD45RA (OX-33) Mouse IgG2a Recombinant Antibody

CD45RA Recombinant Antibody for FC

Host / Isotype

Mouse / IgG2a

Reactivity

rat

Applications

FC

Conjugate

CoraLite®594 Fluorescent Dye

CloneNo.

OX-33

Cat no : CL594-65578

Synonyms

Lca, Ptprc, CD45, RT7, OX-33



Tested Applications

Positive FC detected inrat splenocytes

Recommended dilution

ApplicationDilution
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

CL594-65578 targets CD45RA in FC applications and shows reactivity with rat samples.

Tested Reactivity rat
Host / Isotype Mouse / IgG2a
Class Recombinant
Type Antibody
Immunogen Leukocyte common antigen purified from rat splenocytes
Full Name protein tyrosine phosphatase, receptor type, C
Calculated Molecular Weight143 kDa
GenBank Accession NumberXM_006249910
Gene Symbol CD45
Gene ID (NCBI) 24699
Conjugate CoraLite®594 Fluorescent Dye
Excitation/Emission Maxima Wavelengths588 nm / 604 nm
Form Liquid
Purification MethodProtein A purification
Storage Buffer PBS with 0.09% sodium azide.
Storage ConditionsStore at 2-8°C. Avoid exposure to light.

Background Information

CD45, also known as protein tyrosine phosphatase, receptor type C, is a type I transmembrane protein expressed on the surface of all haematopoietic cells with the exception of erythrocytes and platelets (PMID: 3489673; 28615666). CD45 is a pan-haematopoietic cell marker and has been shown to be essential for T- and B-cell activation and signaling (PMID: 9429890; 16378097). CD45 exists as multiple isoforms due to alternative splicing of three exons (4, 5, and 6, designated A, B, and C) in the extracellular domain (PMID: 12414720). CD45RA is expressed on naïve T cells, B cells, and monocytes (PMID: 1830500; 14687231).

Protocols

Product Specific Protocols
FC protocol for CL594 CD45RA antibody CL594-65578Download protocol
Standard Protocols
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